DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and FVE

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_565456.2	Gene:	FVE / 816471	AraportID:	AT2G19520	Length:	507	Species:	Arabidopsis thaliana

Alignment Length:	207	Identity:	50/207 - (24%)
Similarity:	80/207 - (38%)	Gaps:	43/207 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 CVLVFDAIT-QKEIFKVPDAHTDSVNCIKF--FDERLFATGSDDFTVALWDLRNMK-----QKLR 127
            |::::||.| ...:.||..||...::|:.:  .|:.|..|||.|.||.|:|.|.:.     ..:.
plant   316 CLILWDARTGTNPVTKVEKAHDADLHCVDWNPHDDNLILTGSADNTVRLFDRRKLTANGVGSPIY 380

  Fly   128 VLHGHSNWVKNIEYS-SKDKLLVSSGFDGSIFTWDIN---------SQTEQGLISQRV------- 175
            ...||...|..:::| .|..:..||..||.:..||.:         :::..||..|..
plant   381 KFEGHKAAVLCVQWSPDKSSVFGSSAEDGLLNIWDYDRVSKKSDRAAKSPAGLFFQHAGHRDKVV 445

  Fly   176 -FHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAA 239
             ||.:......|....|.......||.:.|....||.        :||        .|:.:.:..
plant   446 DFHWNASDPWTIVSVSDDCETTGGGGTLQIWRMSDLI--------YRP--------EEEVVAELE 494

  Fly   240 KY-DHVFSKRQK 250
            |: .||.:...|
plant   495 KFKSHVMTCASK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	46/189 (24%)
		WD40	<45..>218	CDD:225201	43/172 (25%)
		WD40 repeat	51..87	CDD:293791	5/16 (31%)
		WD40 repeat	95..129	CDD:293791	12/40 (30%)
		WD40 repeat	136..174	CDD:293791	11/47 (23%)
		WD40 repeat	181..210	CDD:293791	5/28 (18%)
FVE	NP_565456.2	CAF1C_H4-bd	66..134	CDD:403473
		WD40	163..477	CDD:421866	41/160 (26%)
		WD40 repeat	168..217	CDD:293791
		WD40 repeat	222..289	CDD:293791
		WD40 repeat	296..333	CDD:293791	5/16 (31%)
		WD40 repeat	340..383	CDD:293791	12/42 (29%)
		WD40 repeat	389..438	CDD:293791	12/48 (25%)
		WD40 repeat	444..476	CDD:293791	6/31 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910