DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1523 and Wdr55

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_080740.2	Gene:	Wdr55 / 67936	MGIID:	1915186	Length:	388	Species:	Mus musculus

Alignment Length:	151	Identity:	34/151 - (22%)
Similarity:	69/151 - (45%)	Gaps:	4/151 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 FNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLR 120
            |:.||..:|..::.|.:.:.|....:...::..||:..:|.:...||....||.|...:.|||.|
Mouse    93 FSEDGQKLVTVSKDKAIHILDVEQGQLERRISKAHSAPINSVLLVDENALVTGDDTGGIRLWDQR 157

  Fly   121 NMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCR 185
            . :..|..:..|..::.::......|||:::..||.:..::|..:..: |:|:.  .:..|....
Mouse   158 K-EGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFE-LLSEP--QSGDLTSVA 218

  Fly   186 ISPTGDKLVLCTSGGYIMIIH 206
            :...|.|:...:|.|.|.:.:
Mouse   219 LMKYGKKVACGSSEGTIYLFN 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	34/151 (23%)
		WD40	<45..>218	CDD:225201	34/151 (23%)
		WD40 repeat	51..87	CDD:293791	6/30 (20%)
		WD40 repeat	95..129	CDD:293791	11/33 (33%)
		WD40 repeat	136..174	CDD:293791	8/37 (22%)
		WD40 repeat	181..210	CDD:293791	6/26 (23%)
Wdr55	NP_080740.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
		WD 1	37..76
		WD40	<43..338	CDD:225201	34/151 (23%)
		WD40 repeat	43..82	CDD:293791
		WD 2	83..122		6/28 (21%)
		WD40	84..331	CDD:295369	34/151 (23%)
		WD40 repeat	89..126	CDD:293791	6/32 (19%)
		WD 3	126..164		13/38 (34%)
		WD40 repeat	131..166	CDD:293791	11/35 (31%)
		WD 4	167..206		7/39 (18%)
		WD40 repeat	173..207	CDD:293791	7/34 (21%)
		WD 5	209..248		6/33 (18%)
		WD40 repeat	214..251	CDD:293791	6/26 (23%)
		WD 6	251..290
		WD40 repeat	259..296	CDD:293791
		WD 7	293..333
		WD40 repeat	303..323	CDD:293791
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..388
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910