DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1523 and PLRG1

DIOPT Version :9

Sequence 1:NP_651635.2 Gene:CG1523 / 43400 FlyBaseID:FBgn0039601 Length:621 Species:Drosophila melanogaster
Sequence 2:NP_002660.1 Gene:PLRG1 / 5356 HGNCID:9089 Length:514 Species:Homo sapiens


Alignment Length:260 Identity:66/260 - (25%)
Similarity:101/260 - (38%) Gaps:41/260 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 DAGRT----------GAIFNLEFNADGNVVVAA--TERKCVLVFDAITQK--------EIFKVPD 88
            ||.||          ||....:..|..::|:..  |:...::...|.|..        ::::|..
Human   137 DANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVIS 201

  Fly    89 AHTDSVNCIKFF-DERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSG 152
            .|...|.||... ..:.|.|||.|.|:.:|||.:.|.||. |.||.:.|:.:..|::...|.|.|
Human   202 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS-LTGHISTVRGVIVSTRSPYLFSCG 265

  Fly   153 FDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLTTLHKDL 217
            .|..:..||:....   :|.....|.|.:....:.||.|.||.|:......|.......::| .|
Human   266 EDKQVKCWDLEYNK---VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVH-TL 326

  Fly   218 CGFRPGIYRL-MQLGEQYIPQAAKYDHVFSKR-----QKKNRVELVTDFPENNDAEMIMALQIHP 276
            .|....:..: .|..|   ||.....|..:.|     ..|.||.|      .|..:.:.|:.:||
Human   327 SGHTNAVATVRCQAAE---PQIITGSHDTTIRLWDLVAGKTRVTL------TNHKKSVRAVVLHP 382

  Fly   277  276
            Human   383  382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1523NP_651635.2 WD40 43..235 CDD:295369 54/212 (25%)
WD40 <45..>218 CDD:225201 49/193 (25%)
WD40 repeat 51..87 CDD:293791 5/45 (11%)
WD40 repeat 95..129 CDD:293791 14/34 (41%)
WD40 repeat 136..174 CDD:293791 9/37 (24%)
WD40 repeat 181..210 CDD:293791 7/28 (25%)
PLRG1NP_002660.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 135..160 6/22 (27%)
WD40 196..490 CDD:238121 55/201 (27%)
WD 1 202..241 15/38 (39%)
WD40 repeat 209..244 CDD:293791 15/35 (43%)
WD 2 244..283 11/41 (27%)
WD40 repeat 250..286 CDD:293791 8/38 (21%)
WD 3 286..325 10/39 (26%)
WD40 repeat 291..327 CDD:293791 8/36 (22%)
WD 4 328..367 9/41 (22%)
WD40 repeat 334..369 CDD:293791 10/43 (23%)
WD 5 370..410 4/13 (31%)
WD40 repeat 375..410 CDD:293791 3/8 (38%)
WD 6 411..449
WD40 repeat 416..455 CDD:293791
WD 7 460..499
WD40 repeat 465..489 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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