DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and poc1b

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	XP_012814294.1	Gene:	poc1b / 448445	XenbaseID:	XB-GENE-944930	Length:	470	Species:	Xenopus tropicalis

Alignment Length:	176	Identity:	48/176 - (27%)
Similarity:	92/176 - (52%)	Gaps:	19/176 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TGAIFNLEFNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFF-DERLFATGSDD 111
            |..:..:.|::||:..:.|::.|.:..::...|:.::.:.: ||:.|.|.:|. |.||.|:.|||
Frog   102 TAVVRCVNFSSDGHTFITASDDKSIKAWNLHRQRFLYSLTE-HTNWVRCARFSPDGRLIASCSDD 165

  Fly   112 FTVALWDLRNMKQKLRV-----LHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLI 171
            .||.:||:.|   :|.:     ..||||:|   :::.....:.|:|.|.::..|||.:..   |:
Frog   166 KTVRIWDITN---RLCINTFVDYKGHSNYV---DFNPMGTCVASAGVDSTVKVWDIRTNK---LL 221

  Fly   172 SQRVFHASGLMRCRISPTGDKLVLCTSGGYIMIIHHLD---LTTLH 214
            .....|.:|:......|:|:.|:..::.|.:.|:..|:   :.|||
Frog   222 QHYQVHNAGVNSLSFHPSGNYLLTASNDGTVKILDLLEGRLIYTLH 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	48/176 (27%)
		WD40	<45..>218	CDD:225201	48/176 (27%)
		WD40 repeat	51..87	CDD:293791	6/35 (17%)
		WD40 repeat	95..129	CDD:293791	15/39 (38%)
		WD40 repeat	136..174	CDD:293791	8/37 (22%)
		WD40 repeat	181..210	CDD:293791	6/31 (19%)
poc1b	XP_012814294.1	WD40	12..298	CDD:238121	48/176 (27%)
		WD40 repeat	21..58	CDD:293791
		WD40 repeat	64..100	CDD:293791
		WD40 repeat	105..141	CDD:293791	6/35 (17%)
		WD40 repeat	148..183	CDD:293791	15/37 (41%)
		WD40 repeat	190..225	CDD:293791	9/40 (23%)
		WD40 repeat	231..267	CDD:293791	7/35 (20%)
		WD40 repeat	273..297	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910