DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and SPAC1A6.02

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_001342873.1	Gene:	SPAC1A6.02 / 3361484	PomBaseID:	SPAC1A6.02	Length:	361	Species:	Schizosaccharomyces pombe

Alignment Length:	385	Identity:	80/385 - (20%)
Similarity:	131/385 - (34%)	Gaps:	128/385 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RYLSRRESGFHIHRSDDNSLMRRIYSSMNMFNSYHANCWPTDAGRTGAIFNLEFNADGNVVVA-A 66
            |.:|..|||........:.:::...:|....:|.    |..|..:..:.:::....:.::|.| .
pombe    63 RNISVNESGTEFISVGSDGVLKIADTSTGRVSSK----WIVDKNKEISPYSVVQWIENDMVFATG 123

  Fly    67 TERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLRNMKQKLRVLHG 131
            .:..||.|:|..|:..|....:.|.|.::.|..|:||.|...|.|..:::.|.||.|
pombe   124 DDNGCVSVWDKRTEGGIIHTHNDHIDYISSISPFEERYFVATSGDGVLSVIDARNFK-------- 180

  Fly   132 HSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLC 196
                 |.|....:|:.:....     ||.|.:|:.:..     |..|||:           :.|.
pombe   181 -----KPILSEEQDEEMTCGA-----FTRDQHSKKKFA-----VGTASGV-----------ITLF 219

  Fly   197 TSGGY-----------------IMIIHHLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHV 244
            |.|.:                 |..|...|..:|:   .|...|..||:.:    :|.  ||:.:
pombe   220 TKGDWGDHTDRILSPIRSHDFSIETITRADSDSLY---VGGSDGCIRLLHI----LPN--KYERI 275

  Fly   245 FSKRQKKNRVELVTDFPENNDAEMIMALQIHPHCCCMLTRNVSCD--EQSEWTCIHDINEEPVRS 307
            ..:...::.|:.|....|.|..                   |||.  |.:.|         || .
pombe   276 IGQHSSRSTVDAVDVTTEGNFL-------------------VSCSGTELAFW---------PV-D 311

  Fly   308 EDEQDEVEPQPKRKRVSTTLASRSSLNESQDQDT--------------VGLTPRQARRPL 353
            :.|.||               |.||.|...|:|:              ||   .|.::||
pombe   312 QKEGDE---------------SSSSDNLDSDEDSSSDSEFSSPKKKKKVG---NQGKKPL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	44/209 (21%)
		WD40	<45..>218	CDD:225201	39/190 (21%)
		WD40 repeat	51..87	CDD:293791	8/36 (22%)
		WD40 repeat	95..129	CDD:293791	11/33 (33%)
		WD40 repeat	136..174	CDD:293791	7/37 (19%)
		WD40 repeat	181..210	CDD:293791	5/45 (11%)
SPAC1A6.02	NP_001342873.1	WD40	5..>314	CDD:225201	66/326 (20%)
		WD40 repeat	17..54	CDD:293791
		WD40 repeat	64..99	CDD:293791	7/38 (18%)
		WD40 repeat	109..146	CDD:293791	8/36 (22%)
		WD40 repeat	151..185	CDD:293791	13/46 (28%)
		WD40 repeat	193..239	CDD:293791	11/66 (17%)
		WD40 repeat	242..278	CDD:293791	11/44 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910