DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and AgaP_AGAP007626

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	XP_564611.3	Gene:	AgaP_AGAP007626 / 3290403	VectorBaseID:	AGAP007626	Length:	336	Species:	Anopheles gambiae

Alignment Length:	143	Identity:	33/143 - (23%)
Similarity:	66/143 - (46%)	Gaps:	6/143 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 NLEFNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFF-DERLFATGSDDFTVAL 116
            ::.::.||..:.:......:.:||....| :.:..:.|..||..:.|. |.::..|.|||..:.|
Mosquito   181 SIAYSPDGKYIASGAIDGIINIFDVAAGK-VAQTLEGHAMSVRSLCFSPDSQMLLTASDDGHMKL 244

  Fly   117 WDLRNMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGL 181
            :|:.: ...:..|.||::||.::.:|...|...||..|.::..|::   .|:..:.....||..:
Mosquito   245 YDVAH-SDVVGTLSGHASWVLSVSFSGDGKNFASSSSDKTVKIWNV---AERQCLHTFTEHADQV 305

  Fly   182 MRCRISPTGDKLV 194
            ...|.||....::
Mosquito   306 WGVRYSPDSANVI 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	33/143 (23%)
		WD40	<45..>218	CDD:225201	33/143 (23%)
		WD40 repeat	51..87	CDD:293791	5/33 (15%)
		WD40 repeat	95..129	CDD:293791	8/34 (24%)
		WD40 repeat	136..174	CDD:293791	8/37 (22%)
		WD40 repeat	181..210	CDD:293791	3/14 (21%)
AgaP_AGAP007626	XP_564611.3	WD40	58..>332	CDD:225201	33/143 (23%)
		WD40	58..330	CDD:238121	33/143 (23%)
		WD40 repeat	95..133	CDD:293791
		WD40 repeat	136..172	CDD:293791
		WD40 repeat	180..215	CDD:293791	5/34 (15%)
		WD40 repeat	221..257	CDD:293791	9/36 (25%)
		WD40 repeat	263..299	CDD:293791	8/38 (21%)
		WD40 repeat	305..329	CDD:293791	3/14 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810