DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and CG3071

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_569993.1	Gene:	CG3071 / 31213	FlyBaseID:	FBgn0023527	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	44/179 - (24%)
Similarity:	77/179 - (43%)	Gaps:	23/179 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 FNLEFNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERL-FATGSDDFTVA 115
            :...|..||.::.|..|...|.:||. |.:.|.::...||..|:...|..::| .|:..||.:|.
  Fly    85 YGATFRQDGRLLAAGDEEGHVKLFDT-TSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVR 148

  Fly   116 LWDLRNMKQKLRVLHGHSNWVK-NIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHAS 179
            |||:.|.|........|:::|: ...:.....:.||.|:||.|..:|..::|   .:.:.:.|.:
  Fly   149 LWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAET---AVQRTLDHGA 210

  Fly   180 GLMRCRISPTGDKLVLCTSGG---------------YIMIIHHLDLTTL 213
            .:......|.|.  :..::||               .:|..||..:|.|
  Fly   211 PVESMLFLPNGS--IFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCL 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	44/179 (25%)
		WD40	<45..>218	CDD:225201	44/179 (25%)
		WD40 repeat	51..87	CDD:293791	10/34 (29%)
		WD40 repeat	95..129	CDD:293791	11/34 (32%)
		WD40 repeat	136..174	CDD:293791	9/38 (24%)
		WD40 repeat	181..210	CDD:293791	7/43 (16%)
CG3071	NP_569993.1	WD40	<26..283	CDD:225201	44/179 (25%)
		WD40 repeat	87..121	CDD:293791	10/34 (29%)
		WD40	89..318	CDD:238121	44/175 (25%)
		WD40 repeat	126..162	CDD:293791	12/35 (34%)
		WD40 repeat	170..206	CDD:293791	8/38 (21%)
		WD40 repeat	212..247	CDD:293791	4/36 (11%)
		WD40 repeat	254..288	CDD:293791	2/4 (50%)
		WD40 repeat	295..318	CDD:293791
		UTP15_C	352..494	CDD:286472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910