DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and Wdr55

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_001017932.1	Gene:	Wdr55 / 307494	RGDID:	1305640	Length:	384	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	35/151 - (23%)
Similarity:	70/151 - (46%)	Gaps:	4/151 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 FNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLR 120
            |:.||..:|..::.|.:.|.|....:...::..||:..:|.:...||.:..||.|...:.|||.|
  Rat    92 FSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQR 156

  Fly   121 NMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCR 185
            . :..|..:..|..::.::......|||:::..||.:..::|..:..: |:|:.  .:..|....
  Rat   157 K-EGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFE-LLSEP--QSGDLTSVA 217

  Fly   186 ISPTGDKLVLCTSGGYIMIIH 206
            :...|.|:...:|.|.|.:.:
  Rat   218 LMKYGKKVACGSSEGTIYLFN 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	35/151 (23%)
		WD40	<45..>218	CDD:225201	35/151 (23%)
		WD40 repeat	51..87	CDD:293791	7/30 (23%)
		WD40 repeat	95..129	CDD:293791	11/33 (33%)
		WD40 repeat	136..174	CDD:293791	8/37 (22%)
		WD40 repeat	181..210	CDD:293791	6/26 (23%)
Wdr55	NP_001017932.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
		WD 1	36..75
		WD40	<42..337	CDD:225201	35/151 (23%)
		WD40 repeat	42..81	CDD:293791
		WD 2	82..121		7/28 (25%)
		WD40	83..330	CDD:295369	35/151 (23%)
		WD40 repeat	88..125	CDD:293791	7/32 (22%)
		WD 3	125..163		13/38 (34%)
		WD40 repeat	130..165	CDD:293791	11/35 (31%)
		WD 4	166..205		7/39 (18%)
		WD40 repeat	172..206	CDD:293791	7/34 (21%)
		WD 5	208..247		6/33 (18%)
		WD40 repeat	213..250	CDD:293791	6/26 (23%)
		WD 6	250..289
		WD40 repeat	258..295	CDD:293791
		WD 7	293..332
		WD40 repeat	302..322	CDD:293791
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910