DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and Wsb2

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	XP_008767442.1	Gene:	Wsb2 / 288692	RGDID:	1359599	Length:	406	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	43/171 - (25%)
Similarity:	73/171 - (42%)	Gaps:	33/171 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 HTDSVNCIKFF--DERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSG 152
            |.|.|..:.|.  ...:..:.|.|.|:.:|||....::::||.||..||.....|....:|.|:.
  Rat   154 HQDVVRDLSFTPNGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAA 218

  Fly   153 FDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISPTGDKLVLCT-----------SGGYIMIIH 206
            .:.|:|.|.:.|.|   ||.:...|.|.::.|..||....||..:           :|..:..:|
  Rat   219 GEKSVFLWSMRSYT---LIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGERLRSLH 280

  Fly   207 H------LDLTTLH----KDLCGFRPGIY-------RLMQL 230
            |      :|.:.:|    :.:|....|:|       ||:::
  Rat   281 HTQLEAPVDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRI 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	43/171 (25%)
		WD40	<45..>218	CDD:225201	38/150 (25%)
		WD40 repeat	51..87	CDD:293791
		WD40 repeat	95..129	CDD:293791	7/35 (20%)
		WD40 repeat	136..174	CDD:293791	11/37 (30%)
		WD40 repeat	181..210	CDD:293791	8/45 (18%)
Wsb2	XP_008767442.1	WD40 repeat	31..91	CDD:293791
		WD40	32..369	CDD:225201	43/171 (25%)
		WD40	123..362	CDD:238121	43/171 (25%)
		WD40 repeat	159..197	CDD:293791	9/37 (24%)
		WD40 repeat	202..238	CDD:293791	11/38 (29%)
		WD40 repeat	246..291	CDD:293791	9/44 (20%)
		WD40 repeat	298..330	CDD:293791	5/24 (21%)
		WD40 repeat	338..374	CDD:293791
		SOCS_WSB_SWIP	366..404	CDD:239702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910