Protein Alignment CG1523 and AgaP_AGAP010182

DIOPT Version :9

• Sequence 1: NP_651635.2
• Gene: CG1523 / 43400
• FlyBaseID: FBgn0039601
• Length: 621
• Species: Drosophila melanogaster
• Sequence 2: XP_319360.4
• Gene: AgaP_AGAP010182 / 1279603
• VectorBaseID: AGAP010182
• Length: 556
• Species: Anopheles gambiae
• Alignment Length: 655
• Identity: 251/655 - (38%)
• Similarity: 347/655 - (52%)
• Gaps: 136/655 - (20%)

  Fly     1 MERYLSRRESGFHIHRSDDNSLMRRIYSSMNMFNSYHANCWPTDAGR-------TGAIFNLEFNA 58
            :.::..|||.|......|.:::.|.||.|:.     ....| .|.||       .|..|||||:.
Mosquito     3 IHQWCGRRERGLGPRFGDADTIHRTIYRSLE-----PKKIW-NDPGRFPGIVRDYGGAFNLEFSP 61

  Fly    59 DGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFFDERLFATGSDDFTVALWDLRNMK 123
            ||.::|||.::|.:::||.:|:.:|..|.:|||:.||||||.|.::|||.|||.||||||:||:.
Mosquito    62 DGTLLVAACQKKSIVLFDPLTEIQICAVKNAHTECVNCIKFIDHQIFATCSDDTTVALWDIRNLT 126

  Fly   124 QKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRCRISP 188
            .|||.|:|||.||||||||.:|::|:|||||||::.|:||:.||.|.:.:||.|.|||:|.|:||
Mosquito   127 TKLRTLNGHSGWVKNIEYSKRDRMLLSSGFDGSVYGWEINNYTEYGSVYRRVLHTSGLLRSRLSP 191

  Fly   189 TGDKLVLCTSGGYIMIIHHLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHVFSKRQKKNR 253
            ...:|||..|.||::|||.|||..|..||.||.|.:|||||:|.|.||.||::.|:|..::||||
Mosquito   192 DESRLVLSMSSGYLIIIHDLDLANLAGDLEGFYPNVYRLMQVGRQLIPMAARFRHLFYSKRKKNR 256

  Fly   254 VELVTDFPENNDAEMIMALQIHPHCCCMLTRNVSCDEQSEWTCIHDINEEPVRSEDEQDEVE--- 315
            :|||||||.||:.|||.:|.|||...|.||||||.||.:||:.:|||.|.|...|.::||.|
Mosquito   257 IELVTDFPPNNNPEMISSLAIHPQGWCTLTRNVSSDEMTEWSVVHDIQELPHDEESDEDEEELAE 321

  Fly   316 -PQPKRKRVSTTLASRSSLNESQDQDTVGLTPRQARRPLRVSSVQVFQLDN----SGAGRGASDN 375
             .|.:|:..:.....||:|..|:..     .|.:|:......|.|.....|    :|.||..
Mosquito   322 REQNRREEDNDQAEDRSNLVTSRSS-----PPHEAQHVEAGPSGQQPPAANVRRQNGRGRRV--- 378

  Fly   376 PSVLT----RSDSFIPDIWAAEVTVQER------AIRQNRARVSNNHVSGYNFVYAISSGVLPLR 430
              ::|    ||::...|:||.|||.:||      .:|.||.:           :|.|.|||
Mosquito   379 --MITRRNLRSENASTDVWATEVTFRERKNMPSPQVRNNRGQ-----------IYGIVSGV---- 426

  Fly   431 QLGANSLMGSSTSPRPLTTPPPTESNQSSSSSSSSSSSSSSSSSSNNSDTTVRLEIGNRLRLRSF 495
                                         |||:|:..:.:....:|
Mosquito   427 -----------------------------SSSASTGYTGAGRKRAN------------------- 443

  Fly   496 NSPVTTPTFKENGHSILVNAKKLLYYAAETNTKPGFIKEPGFSADGRVVCSPYGNGVRLFGYSED 560
                         ..|..|..::|||..||.|..|||:|..||.|||::|||:.:|.||..::|:
Mosquito   444 -------------EKICKNVPRMLYYMQETITDQGFIRESCFSPDGRIICSPHDHGFRLLAFNEN 495

  Fly   561 CCDY---------PKCQAFEEVKSKPRKLVELAKITEHQDVVLCAKFSPREPLLVTGCNGGEVTW 616
            |.:.         .|.|...|||.|..          |..:|:.::||||.|||||||..|::.|
Mosquito   496 CNELQHATGIWRNEKAQQLHEVKRKQC----------HSSLVVSSQFSPRFPLLVTGCLLGKIVW 550

  Fly   617 YRPNL 621
            ::|.|
Mosquito   551 HQPAL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	109/198 (55%)
		WD40	<45..>218	CDD:225201	97/179 (54%)
		WD40 repeat	51..87	CDD:293791	15/35 (43%)
		WD40 repeat	95..129	CDD:293791	23/33 (70%)
		WD40 repeat	136..174	CDD:293791	22/37 (59%)
		WD40 repeat	181..210	CDD:293791	15/28 (54%)
AgaP_AGAP010182	XP_319360.4	WD40	<52..>223	CDD:225201	96/170 (56%)
		WD40 repeat	55..91	CDD:293791	16/35 (46%)
		WD40	<59..>222	CDD:295369	91/162 (56%)
		WD40 repeat	98..134	CDD:293791	24/35 (69%)
		WD40 repeat	139..178	CDD:293791	22/38 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	250	1.000	Domainoid score	I4834
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	403	1.000	Inparanoid score	I3933
OMA	1	1.010	-	-		QHG49939
OrthoDB	1	1.010	-	-		D1068414at2759
OrthoFinder	1	1.000	-	-		FOG0007319
OrthoInspector	1	1.000	-	-		otm50994
Panther	1	1.100	-	-	LDO	PTHR14588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5430
TreeFam	1	0.960	-	-
	12	11.940