DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1523 and Coro2a

DIOPT Version :9

Sequence 1:NP_651635.2 Gene:CG1523 / 43400 FlyBaseID:FBgn0039601 Length:621 Species:Drosophila melanogaster
Sequence 2:NP_849224.2 Gene:Coro2a / 107684 MGIID:1345966 Length:543 Species:Mus musculus


Alignment Length:432 Identity:92/432 - (21%)
Similarity:155/432 - (35%) Gaps:129/432 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 HTDSVNCIKF--FDERLFATGSDDFTVALWDL------RNMKQKLRVLHGHSNWVKNIE-YSSKD 145
            |..:|..||:  |::...|:.|:|.|:.:|::      ||:....:.|.||:..|..:| :.:..
Mouse   100 HRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGLVEWHPTTA 164

  Fly   146 KLLVSSGFDGSIFTWDINSQTEQGLISQRV----FHASGLMRCRISPTGDKLVLCTSGGYIMIIH 206
            .:|.|:|:|..:..|  |..|:..:|:..|    .|...::....:..|..|........|.|:.
Mouse   165 NILFSAGYDYKVMVW--NLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVD 227

  Fly   207 HLDLTTLHKDLCGFRPGIYRLMQLGEQYIPQAAKYDHVFSKRQKKNRV--------ELVTDFPEN 263
            .             |.||          :.|.|.|     |..:.|:|        .|.|.....
Mouse   228 P-------------RLGI----------VLQEASY-----KGHRANKVLFLGSLKKLLSTGTSRW 264

  Fly   264 NDAEMIMALQIHPHCCCMLTRNVSCDEQSEWTCIHDINEEPVRSED------------EQD---- 312
            |:.:|.:..|          .|:|.               |:..||            :.|    
Mouse   265 NNRQMALWDQ----------ENLSV---------------PLTEEDLDGSSGVLFPFFDSDTSML 304

  Fly   313 -------------EVEPQPKRKRVSTTLASRSSLNESQDQDTVGLTPRQARRPLRVSSVQVFQLD 364
                         ||..:   |...|.|....|.|   .|..:|:.|   :|.|.|||.::|:..
Mouse   305 YIVGKGDGNIRYYEVSME---KPHLTYLTEYRSYN---PQKGIGIMP---KRGLDVSSCEIFRFY 360

  Fly   365 NSGAGRGASDNPSVLT--RSDSFIPDIW----AAE--VTVQERAIRQNRARVSNNHVSGYNFVYA 421
            .....:...:..|::.  ||:|:..||:    ||:  :|..|.....||..:..:...|...   
Mouse   361 KLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMSLRPGSEL--- 422

  Fly   422 ISSGVLPLRQLGANSLMGSSTSPRPL--TTPPPTESNQSSSS 461
            :.|..||..:..:||::  ..||:||  ...|..:.:|:..|
Mouse   423 LDSQTLPPERPLSNSMV--QVSPQPLEPMKQPAEDGDQAPFS 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1523NP_651635.2 WD40 43..235 CDD:295369 34/157 (22%)
WD40 <45..>218 CDD:225201 31/140 (22%)
WD40 repeat 51..87 CDD:293791
WD40 repeat 95..129 CDD:293791 10/41 (24%)
WD40 repeat 136..174 CDD:293791 10/38 (26%)
WD40 repeat 181..210 CDD:293791 4/28 (14%)
Coro2aNP_849224.2 WD40 29..536 CDD:392136 92/432 (21%)
WD40 repeat 59..99 CDD:293791
WD40 repeat 105..149 CDD:293791 11/43 (26%)
WD40 repeat 154..196 CDD:293791 11/43 (26%)
WD40 repeat 203..238 CDD:293791 8/57 (14%)
WD40 repeat 244..285 CDD:293791 10/65 (15%)
WD40 repeat 292..331 CDD:293791 6/41 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.