DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1523 and Poc1b

DIOPT Version :9

Sequence 1:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	XP_002729827.2	Gene:	Poc1b / 100362836	RGDID:	2323942	Length:	477	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	69/283 - (24%)
Similarity:	118/283 - (41%)	Gaps:	47/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TGAIFNLEFNADGNVVVAATERKCVLVFDAITQKEIFKVPDAHTDSVNCIKFF-DERLFATGSDD 111
            |..:.:::|:|||..:|.|:|.|.:.|:....|:.::.: ..||..|.|.||. |.||..:.|:|
  Rat   102 TAPVRSVDFSADGQFLVTASEDKSIKVWSMYRQRFLYSL-YRHTHWVRCAKFSPDGRLIVSCSED 165

  Fly   112 FTVALWDLRNMKQKLRVLHGHSNWVKNIEYSSKDKLLVSSGFDGSIFTWDINSQTEQGLISQRVF 176
            .|:.:||..: ||.:........:...:::|.....:.|:|.|.::..|||....   |:.....
  Rat   166 KTIKIWDTTS-KQCVNNFSDSVGFANFVDFSPNGTCIASAGSDHAVRIWDIRMNR---LLQHYQV 226

  Fly   177 HASGLMRCRISPTGDKLVLCTSGGYIMIIHHLDLTTLHKDLCGFRPGIYRLM-QLGEQYIPQAAK 240
            |:.|:......|:|:.||..:|.|.:.|:          ||...|. ||.|. ..|..:....:|
  Rat   227 HSCGVNCLSFHPSGNSLVTASSDGTVKIL----------DLVEGRL-IYTLQGHTGPVFTVSFSK 280

  Fly   241 YDHVFSKRQKKNRVELV--TDF-------PENNDAEMIMALQIHPHCCCMLTRNVSCDEQSEWTC 296
            ...:|:......:| ||  |.|       |...:.:. :.|:..||...:..|.
  Rat   281 DGELFTSGGADAQV-LVWRTSFNQVHYRDPSKRNLKR-LHLEASPHLLDIYPRT----------- 332

  Fly   297 IHDINEEPVRSEDEQDEVEPQPK 319
                   |...||:::.:|..||
  Rat   333 -------PHGHEDKRETIEINPK 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1523	NP_651635.2	WD40	43..235	CDD:295369	51/188 (27%)
		WD40	<45..>218	CDD:225201	45/170 (26%)
		WD40 repeat	51..87	CDD:293791	10/35 (29%)
		WD40 repeat	95..129	CDD:293791	13/34 (38%)
		WD40 repeat	136..174	CDD:293791	8/37 (22%)
		WD40 repeat	181..210	CDD:293791	7/28 (25%)
Poc1b	XP_002729827.2	WD40	10..298	CDD:238121	56/212 (26%)
		WD40	14..>300	CDD:225201	56/214 (26%)
		WD40 repeat	21..58	CDD:293791
		WD40 repeat	64..100	CDD:293791
		WD40 repeat	105..141	CDD:293791	10/36 (28%)
		WD40 repeat	148..183	CDD:293791	13/35 (37%)
		WD40 repeat	189..225	CDD:293791	8/38 (21%)
		WD40 repeat	231..267	CDD:293791	12/46 (26%)
		WD40 repeat	273..297	CDD:293791	4/24 (17%)
		Ribosomal_S10	<331..365	CDD:294222	7/36 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910