DRSC/TRiP Functional Genomics Resources

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Protein Alignment wdn and ZNF566

DIOPT Version :9

Sequence 1:NP_476900.1 Gene:wdn / 43398 FlyBaseID:FBgn0005642 Length:869 Species:Drosophila melanogaster
Sequence 2:NP_001138815.1 Gene:ZNF566 / 84924 HGNCID:25919 Length:419 Species:Homo sapiens


Alignment Length:232 Identity:80/232 - (34%)
Similarity:117/232 - (50%) Gaps:17/232 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   284 EVAKHEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGS-MWM 347
            :.|.|| ..|.:...|.|.||.:.|...:.|..|.|.|  .|:|..  :|.:|||....|| :..
Human   186 QFATHE-IIHTIEKPYECKECGKSFRHPSRLTHHQKIH--TGKKPF--ECKECGKTFICGSDLTR 245

  Fly   348 HRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTR 412
            |.:||:..|.|:|..||:.|....|.|.|.|||:.||||||.||.|.|...|:..:||:.|...:
Human   246 HHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEK 310

  Fly   413 SYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPR 477
            .|.|::||..:.....|..|..:|..::|:.|..|:|:|.|.|.|.:|..||||.:|::|..|.:
Human   311 PYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGK 375

  Fly   478 DFTNFPNWLKHTRRRHKV--DHKTGEHLENIPSYCSK 512
            .::.....:.|    |::  ..|..|:.|     |.|
Human   376 AYSQSSQLISH----HRIHTSEKPYEYRE-----CGK 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdnNP_476900.1 C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
RPB9 333..425 CDD:224510 39/92 (42%)
C2H2 Zn finger 333..352 CDD:275368 7/19 (37%)
zf-H2C2_2 344..369 CDD:290200 10/25 (40%)
zf-C2H2 358..380 CDD:278523 9/21 (43%)
C2H2 Zn finger 360..380 CDD:275368 8/19 (42%)
zf-H2C2_2 372..395 CDD:290200 15/22 (68%)
zf-C2H2 386..408 CDD:278523 10/21 (48%)
C2H2 Zn finger 388..436 CDD:275368 15/47 (32%)
zf-H2C2_2 400..425 CDD:290200 7/24 (29%)
C2H2 Zn finger 416..433 CDD:275368 4/16 (25%)
zf-H2C2_2 429..453 CDD:290200 8/23 (35%)
C2H2 Zn finger 444..464 CDD:275368 8/19 (42%)
zf-H2C2_2 457..481 CDD:290200 9/23 (39%)
C2H2 Zn finger 472..493 CDD:275368 3/20 (15%)
ZNF566NP_001138815.1 KRAB 6..66 CDD:214630
KRAB 6..45 CDD:279668
COG5048 <154..330 CDD:227381 55/148 (37%)
zf-C2H2 200..222 CDD:278523 8/21 (38%)
C2H2 Zn finger 202..222 CDD:275368 7/19 (37%)
zf-H2C2_2 215..237 CDD:290200 10/25 (40%)
C2H2 Zn finger 230..250 CDD:275368 7/19 (37%)
zf-H2C2_2 242..267 CDD:290200 9/24 (38%)
COG5048 <254..405 CDD:227381 56/159 (35%)
C2H2 Zn finger 258..278 CDD:275368 8/19 (42%)
zf-H2C2_2 270..295 CDD:290200 16/24 (67%)
C2H2 Zn finger 286..306 CDD:275368 8/19 (42%)
zf-H2C2_2 298..323 CDD:290200 7/24 (29%)
C2H2 Zn finger 314..334 CDD:275368 5/19 (26%)
zf-H2C2_2 327..351 CDD:290200 8/23 (35%)
C2H2 Zn finger 342..362 CDD:275368 8/19 (42%)
zf-H2C2_2 354..379 CDD:290200 9/24 (38%)
C2H2 Zn finger 370..390 CDD:275368 4/23 (17%)
C2H2 Zn finger 398..417 CDD:275368 3/11 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4021
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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