Protein Alignment CG10000 and GALNT4

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 188/607 - (30%)
• Similarity: 290/607 - (47%)
• Gaps: 100/607 - (16%)

  Fly     5 GKYCGPRHCSFYIIAFLICQLFFLVIFIRNDDASS----ANEL----LSFMNESEESDHLDWRVF 61
            ||.|       .::|||.....|:.:.:....||:    |.||    ||.:.::.|...   |..
Human     9 GKSC-------LLLAFLTVAYIFVELLVSTFHASAGAGRARELGSRRLSDLQKNTEDLS---RPL 63

  Fly    62 ISHTPETSE-------------------------DFYQYNIHLSNALGLIRKLPVTRHHSCTTRN 101
            ....|..|.                         :.|..||:||:.:.|.|.:...|.:.|.::.
Human    64 YKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQK 128

  Fly   102 ---SILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLK 163
               ..||     ..||:|:|:|||.|.|||||.|:|..||...|.|:|||||.|.| |.|...|:
Human   129 FNYRTLP-----TTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDR-VYLKTQLE 187

  Fly   164 RWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLAL 228
            .::..:  .|.||    :|..:|.||:.:|..||:.|:|..:.|||.|||.|.|||||||||:..
Human   188 TYISNL--DRVRL----IRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGR 246

  Fly   229 NTNLAVSPLLDPIDPTTLS-YRKGNELLKGGFDWSLHFHW---LKRQLTNQESLEMPYQSPAFAG 289
            :....|.|::|.||..|.. |.:..|.:.|||||.|.|.|   .|::...:.|...|.:||..||
Human   247 DETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAG 311

  Fly   290 GVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQS 354
            |:..:|:::|..||:::..:::||||::||:.::|.|||::||.|||.:||:|.:|..:
Human   312 GLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPY------ 370

  Fly   355 DRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQR---MRKERRCHPFE 416
                  |:..:|.|:...||.|:||||..||...|.||:    ..|.::..   :|:..||..|:
Human   371 ------ARPNFLQNTARAAEVWMDEYKEHFYNRNPPARK----EAYGDISERKLLRERLRCKSFD 425

  Fly   417 WYLRHVSPELRMHFDELSATGTLRN---EDRCVHARQKDSQPI-----LASCYLSDITQWSMLRQ 473
            |||::|.|.|.:..|.....|.:|:   ...|:.....|:.|.     |..|:.....|:.....
Human   426 WYLKNVFPNLHVPEDRPGWHGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGNQFFEYTS 490

  Fly   474 SGQL--STHRELCLAVGFGMR-IALEPCGRNE-TVRRSQRW--VRLGTHLLHAESHLCLD---NP 529
            :.::  ::..|||..|..... :.::.|.::. .|..:..|  ...|| :.|..|.|||.   .|
Human   491 NKEIRFNSVTELCAEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGT-IFHPHSGLCLSAYRTP 554

  Fly   530 L-KDRLEMSTCRSHAVSQSFQF 550
            . :..::|.||.:...:|.:.|
Human   555 EGRPDVQMRTCDALDKNQIWSF 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	127/315 (40%)
		Ricin_B_lectin	435..548	CDD:279046	27/130 (21%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		57/120 (48%)
		pp-GalNAc-T	138..432	CDD:133004	127/316 (40%)
		Catalytic subdomain B	303..365		27/61 (44%)
		Ricin_B_lectin	446..574	CDD:395527	27/128 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820