DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10000 and Galnt5

DIOPT Version :10

Sequence 1:NP_651630.3 Gene:CG10000 / 43394 FlyBaseID:FBgn0039596 Length:558 Species:Drosophila melanogaster
Sequence 2:NP_113984.1 Gene:Galnt5 / 83627 RGDID:620361 Length:930 Species:Rattus norvegicus


Alignment Length:509 Identity:168/509 - (33%)
Similarity:260/509 - (51%) Gaps:88/509 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 YNIHLSNALGLIRKLPVTRHHSCTTR--NSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRS 137
            :|::||:.:.:.|.:..||...|..:  ::.||     ..|:::.|.:|..|.|||::.|:|:||
  Rat   454 FNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLP-----TTSIIMCFVDEVWSALLRSVHSVLNRS 513

  Fly   138 PEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASG 202
            |...:.|::||||.|.:|. |..:|.::|     |::. .:..||.:||.|||.:|..||..|:|
  Rat   514 PPHLIKEILLVDDFSTKDY-LKANLDKYM-----SQFP-KVRILRLKERHGLIRARLAGAQNATG 571

  Fly   203 RYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHW 267
            ..:.|||||.|.|.|||||||||:.||......|:::.|:...:||...:...:|.|.|.::|.|
  Rat   572 DVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGW 636

  Fly   268 --------LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLW 324
                    .|..:...:.:    :.|..|||:..:.:.:|.:||:::|.|.:||||::||:.|:|
  Rat   637 RTIPPDVIAKNGIKETDII----RCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVW 697

  Fly   325 LCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRP 389
            :|||:|||:||||:|||||..:.:.||  .||     .:|...|...:||.||||||.:||... 
  Rat   698 MCGGEIEIIPCSRVGHIFRNDNPYSFP--KDR-----MKTVERNLVRVAEVWLDEYKELFYGHG- 754

  Fly   390 AARRIPLDHTYD---------ELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN--ED 443
                   ||..|         :.:.:||:.:|..|:|||.:|.|:|:.  ..:.|:|...|  ..
  Rat   755 -------DHLIDQGLDVGNLTQQRELRKKLKCQSFKWYLDNVFPDLKA--PVVRASGVFINLALG 810

  Fly   444 RCVHARQKDSQPILASCYLSDITQWSMLRQSG----QLSTHRELCLA-VGFGMRIALEPC-GRNE 502
            :||..  |:...:|..|..|     |.|:|..    :|..|.|.|:| :.....:.|.|| .||.
  Rat   811 KCVSI--KNITVVLEDCDGS-----SELQQFNYTWVRLIKHGEWCVAPIPDKGSLTLYPCDNRNN 868

  Fly   503 TVRRSQRWVRLGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSFQFALEMEG 556
            .:    :|:.......|.|        |.|         |.|.:|:|..|.|||
  Rat   869 RL----KWLHRSASAFHPE--------LVD---------HIVFESYQQLLCMEG 901

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10000NP_651630.3 pp-GalNAc-T 113..422 CDD:133004 121/325 (37%)
beta-trefoil_Ricin-like 432..550 CDD:483949 30/125 (24%)
Galnt5NP_113984.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 163..210
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 344..377
Catalytic subdomain A 485..594 51/120 (43%)
pp-GalNAc-T 489..790 CDD:133004 121/326 (37%)
Catalytic subdomain B 654..716 30/65 (46%)
beta-trefoil_Ricin-like 796..928 CDD:483949 35/134 (26%)
Blue background indicates that the domain is not in the aligned region.

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