DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt9

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_001338018.1	Gene:	galnt9 / 797549	ZFINID:	ZDB-GENE-060526-21	Length:	604	Species:	Danio rerio

Alignment Length:	512	Identity:	156/512 - (30%)
Similarity:	253/512 - (49%)	Gaps:	72/512 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ETSEDF--YQYNIHLSNALGLIRKLPVTRHHSC--TTRNSILPAPLEANVSVVISFHNEARSMLL 127
            ||...|  |.||..||:.:.|.|.:|..|...|  .|.:..||     .:|||..|.|||.|::|
Zfish   110 ETEGRFEEYGYNAQLSDRISLDRNIPDYRPKKCKQLTYSDDLP-----QISVVFIFVNEALSVIL 169

  Fly   128 RTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWS 192
            |::.|:::.:|...|.|:|||||.|. .|.|..:|..::    ..||...:..:||.:|.|||.:
Zfish   170 RSVHSMVNHTPAHLLKEIILVDDNSD-SVELKFNLDHYV----NKRYPGLVKIVRNSKREGLIRA 229

  Fly   193 RNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKG 257
            |..|.:.|:...|.|.|:|.|.|..|.||:|.|:..:....:.|.:|.|...|...::......
Zfish   230 RIHGWNAATAPVVGFFDAHVEFNTAWAEPILTRVKEDHTRIILPAIDNIKYNTFEVQQYANAAH- 293

  Fly   258 GFDWSLHFHWLKRQLTNQESLE-----MPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESI 317
            |::|.|   |....:..|:.|:     .|.::||..|...::.||:|.::|..:|.::::|||:|
Zfish   294 GYNWGL---WCMYIIPPQDWLDRGDETAPIRTPAMIGCSFVVDREYFGEIGLLDPGMEVYGGENI 355

  Fly   318 ELAIKLWLCGGQIEIVPCSRIGHIFRRRHAF--DFPPQSDRQLSPAQETYLHNSKIIAESWLDEY 380
            ||.:::|.|||.:|::||:|:.||.|.:..:  |....:.|           |:...||.|:||:
Zfish   356 ELGMRVWQCGGSMEVLPCARVAHIERTKKPYNNDIDYYAKR-----------NALRAAEVWMDEF 409

  Fly   381 KNMFYALRPAARRIPLDH------TYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTL 439
            |:..|    .|..||:::      ...|...:||:..|..|.|||.||.||:|::.:.:: .|.:
Zfish   410 KSHVY----MAWNIPMNNPGVDFGDVSERVALRKKMNCKSFRWYLEHVYPEMRIYNNTIT-YGEV 469

  Fly   440 RNEDR---CV-HARQKDSQPILASCY--LSDITQWSM--LRQSGQLSTHREL----CLA-VGFGM 491
            ||...   |: ...::|.:.||..|:  .|.:.:::.  |.|.|.|.:...|    ||. .|.|.
Zfish   470 RNSKASGYCLDQGSEEDERAILYPCHGMSSQLARYTTEGLLQLGPLGSTTFLPDTKCLVDDGRGR 534

  Fly   492 RIALEPCGRNETVRRSQR-W--VRLGTHLLHAESHLCLDNPL-KD-----RLEMSTC 539
            ..:|:.|  :...|.||| |  .:.|. ::..::..||:..: ||     ||.:..|
Zfish   535 TPSLKKC--DSVTRSSQRLWDFTQNGP-IISRDTGRCLEVEMSKDANFGLRLVVQRC 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	102/321 (32%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	33/127 (26%)
galnt9	XP_001338018.1	pp-GalNAc-T	155..454	CDD:133004	103/322 (32%)
		Ricin_B_lectin	465..593	CDD:279046	33/128 (26%)
		RICIN	467..595	CDD:238092	33/125 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900