Protein Alignment CG10000 and GALNT14

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 171/461 - (37%)
• Similarity: 257/461 - (55%)
• Gaps: 56/461 - (12%)

  Fly   113 SVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRL- 176
            |::|:|||||||.|||||.|:|:|:|...:.|:|||||.|...    ||.|:.:        :|
Human   119 SIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDP----DDCKQLI--------KLP 171

  Fly   177 GLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPI 241
            .:..|||.||.||:.||.|||.:|.|..:.|||||||||..||:|||.|:..:....|.|::|.|
Human   172 KVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYTRVVCPVIDII 236

  Fly   242 DPTTLSYRKGNELLKGGFDWSLHFHWLKRQLTNQESLEM-----PYQSPAFAGGVLMMSREWFLK 301
            :..|.:|.:....|:|||||||||.|  .||:.::....     |.::|..|||:.::.:.||..
Human   237 NLDTFTYIESASELRGGFDWSLHFQW--EQLSPEQKARRLDPTEPIRTPIIAGGLFVIDKAWFDY 299

  Fly   302 LGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYL 366
            ||.::..:.|||||:.|::.::|:|||.:|||||||:||:||::|.:.||..:       ..||:
Human   300 LGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGN-------ANTYI 357

  Fly   367 HNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHFD 431
            .|:|..||.|:||||..:||.||.|...|..:....|. :||..||..|:|||.::.|||.:..:
Human   358 KNTKRTAEVWMDEYKQYYYAARPFALERPFGNVESRLD-LRKNLRCQSFKWYLENIYPELSIPKE 421

  Fly   432 ELSATGTLRNEDRCVHARQKDSQPI----LASC-------YLSDITQWSMLRQSGQLSTHRELCL 485
            .....|.:|...:|:.::::::|..    |:.|       ..|.:..::..:|..|    .||||
Human   422 SSIQKGNIRQRQKCLESQRQNNQETPNLKLSPCAKVKGEDAKSQVWAFTYTQQILQ----EELCL 482

  Fly   486 AVGF---GMRIALEPCGRNETVRRSQRWVRLGTHLLHAESHLCLDNPL-------KDRLEMSTCR 540
            :|..   |..:.|..|...:.   .|:|.:.|:|:.|..||||||..:       ...:.::.|.
Human   483 SVITLFPGAPVVLVLCKNGDD---RQQWTKTGSHIEHIASHLCLDTDMFGDGTENGKEIVVNPCE 544

  Fly   541 SHAVSQ 546
            |..:||
Human   545 SSLMSQ 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	136/314 (43%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	32/136 (24%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	136/315 (43%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	32/140 (23%)