DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt14

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001072369.1	Gene:	galnt14 / 779822	XenbaseID:	XB-GENE-992201	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	555	Identity:	198/555 - (35%)
Similarity:	300/555 - (54%)	Gaps:	87/555 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ESEESD-------HLDW----------RVFISHTPETSED---FYQYNIHLSNALGLIRKLPVTR 93
            |:|||:       .:||          |...:......||   .|.:|...|..:...|.:..||
Frog    33 EAEESEGDPAKEGDVDWDDLWDQFDERRYLNAQKWRPGEDPYRLYAFNQRESERIPSDRAIKDTR 97

  Fly    94 HHSCTTRN--SILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQR-- 154
            |:.||..:  |.||.     .||:|:|||||||.|||||.|:|:|:|...:||::||||.|..
Frog    98 HYRCTELHYQSDLPP-----TSVIITFHNEARSTLLRTIRSVLNRTPMHLIHEILLVDDFSDNLD 157

  Fly   155 DVTLLDDLKRWMGGVFGSRYRLGLTFLRNQER-MGLIWSRNRGASLASGRYVLFLDSHCEVNEGW 218
            |..||..|.:             :..|||::| .|||.||.|||.:|....:.|||||||||:.|
Frog   158 DCRLLSKLPK-------------VRCLRNEQREAGLIRSRVRGAGVAQAAVLTFLDSHCEVNKDW 209

  Fly   219 LEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWLKRQLTNQESLEM--- 280
            |.|||.|:..:....|||::|.|:..|.:|...:..|:|||||||||.|  .||:.::..:.
Frog   210 LPPLLHRIKEDPTRVVSPVIDIINLDTFAYIAASSDLRGGFDWSLHFKW--EQLSAEQKAKRLDP 272

  Fly   281 --PYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFR 343
              |.::|..|||:.::.:.||..||.::..:.|||||:.|::.::|:|||.:||:||||:||:||
Frog   273 TEPIKTPVIAGGLFVIEKSWFNHLGKYDTAMDIWGGENFEISFRVWMCGGSLEIIPCSRVGHVFR 337

  Fly   344 RRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQR--- 405
            ::|.:.||..:       ..||:.|:|..||.|:||:||.:||.||||:..|    |.::|:
Frog   338 KKHPYVFPEGN-------ANTYIKNTKRTAEVWMDEFKNHYYAARPAAQGRP----YGDIQKRLS 391

  Fly   406 MRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNEDRCVHARQKDSQP-----ILASCY---- 461
            :|:..:|..|:|||.:|.|||::..:.||.:|.:|...||:.: ||...|     .|..|.
Frog   392 LRRTLKCRSFKWYLENVYPELQIPAESLSKSGIIRQRQRCIES-QKTEGPEPPSLNLVPCSSLKG 455

  Fly   462 LSDITQWSMLRQSGQLSTHRELCLAVGF---GMRIALEPCGRNETVRRSQRWVRLGTHLLHAESH 523
            :|..:|..:..|..|:| ...||::|..   |.::.|.||...:   ..|||.::|:|:.|..|.
Frog   456 VSPQSQEWVYTQVQQIS-QGPLCMSVHTLFPGTQVVLLPCREGD---GKQRWSKVGSHIEHMASR 516

  Fly   524 LCLDNPL------KDRLEMSTCRSHAVSQSFQFAL 552
            .|||..:      ...:.::.|.:.|::|.::..|
Frog   517 FCLDTDIIGDTEESREIVINPCETTAITQRWEMVL 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	136/319 (43%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	34/130 (26%)
galnt14	NP_001072369.1	Abhydrolase	1..>78	CDD:304388	9/44 (20%)
		Glyco_tranf_2_3	111..338	CDD:290369	107/246 (43%)
		pp-GalNAc-T	114..409	CDD:133004	136/320 (43%)
		Ricin_B_lectin	422..547	CDD:279046	34/129 (26%)
		RICIN	423..549	CDD:238092	34/130 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	1	1.000	-	-		FOG0001204
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010