Protein Alignment CG10000 and galnt12

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_688194.1
• Gene: galnt12 / 559736
• ZFINID: ZDB-GENE-060503-704
• Length: 578
• Species: Danio rerio
• Alignment Length: 606
• Identity: 176/606 - (29%)
• Similarity: 285/606 - (47%)
• Gaps: 131/606 - (21%)

  Fly     8 CGPRHCSFYII----AFLICQLFFLVIFIRN--------------DDASSANEL----------- 43
            ||.|..|.:|:    ||::..|    :|.||              |:..:.:|.
Zfish     4 CGRRSRSKFILYIVGAFVVGYL----VFHRNTQSDVGLAKIREVPDEHKNVDEQFLKRPVYEKPA 64

  Fly    44 --LSFMNESEESDHLDWRVFISHTPETSEDFYQYNIHLSNALGLIRKL-----PVTRHHSCTTRN 101
              ::.:.|...:..||.........|.|...:|.|.::|:.:.|.|:|     |:.|:    .:.
Zfish    65 LDVNALGEMGRAVKLDLSGEEKREEEESIKKHQINTYVSDRISLHRRLAERWNPLCRN----LKY 125

  Fly   102 SILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWM 166
            ..|..|   ..||||:|:|||.|.||||:.|:|..||:..|:|:|||||.|.|: .|.:.|:.::
Zfish   126 DYLSLP---TTSVVIAFYNEAWSTLLRTVHSVLETSPDLLLNEVILVDDYSDRE-HLKEPLENYI 186

  Fly   167 GGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTN 231
            ..:  .:.||    :|.::|.||:.:|..|||:|:|..:.|||.|||.:||||||||:|:....:
Zfish   187 ADL--KKVRL----IRARKREGLVRARLLGASIATGEVLTFLDCHCECHEGWLEPLLQRIKEEPS 245

  Fly   232 LAVSPLLDPIDPTTLSYRKGN--ELLKGGFDWSLHFHW-------LKRQLTNQESLEMPYQSPAF 287
            ..|.|::|.||..|..| .||  |...|||||.|.|.|       .||:....:.:    :||..
Zfish   246 AVVCPVIDVIDWNTFQY-LGNPGEPQIGGFDWRLVFTWHSIPEHEQKRRSAATDVV----RSPTM 305

  Fly   288 AGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPP 352
            |||:..:::::||.||:::..:::||||::|.:.::|.|||.:||.|||.:||:|.::..:
Zfish   306 AGGLFAVNKKYFLYLGTYDTGMEVWGGENLEFSFRIWQCGGSLEIHPCSHVGHVFPKKAPY---- 366

  Fly   353 QSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKER---RCHP 414
                    ::...|.||...||.|:|::|.::|...|.||.    ..|.::...||.|   ||..
Zfish   367 --------SRNKALANSVRAAEVWMDDFKEVYYHRSPHARL----EAYGDVTDRRKLRMRLRCKD 419

  Fly   415 FEWYLRHVSPELRMHFDELSATGTLRNE---DRCVHARQKDSQPILASCYLSDITQWSMLRQSGQ 476
            |.|:|.::.|::::..|:....|.|:|:   :.|......|...|.
Zfish   420 FRWFLDNIYPDIQVPEDKPGMFGMLKNKGMTNYCFDYNPPDEHKIA------------------- 465

  Fly   477 LSTHRELCLAVGFGMRIALEPC---GRNETVRRSQ-RWVRLGTHLLHAESHLCLDNPLKDRLEMS 537
                         |.|:.|.||   |:|:....|. :.:|..|   ...:...:.:|:...|.|:
Zfish   466 -------------GHRVILYPCHGMGQNQFFEYSTLQEIRYNT---RDPAGCVVADPVSTFLTMN 514

  Fly   538 TCRS--HAVSQSFQFALEMEG 556
            .|..  .||.:..:|....:|
Zfish   515 LCSKPREAVPEDQKFLFREDG 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	122/320 (38%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	22/126 (17%)
galnt12	XP_688194.1	pp-GalNAc-T	134..428	CDD:133004	122/321 (38%)
		beta-trefoil_Ricin_GALNT12	438..577	CDD:467349	24/133 (18%)