DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt1

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_009290644.1	Gene:	galnt1 / 559073	ZFINID:	ZDB-GENE-030131-2360	Length:	557	Species:	Danio rerio

Alignment Length:	497	Identity:	162/497 - (32%)
Similarity:	281/497 - (56%)	Gaps:	47/497 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSP 138
            |:|:..|..:.|.|.||..|...|.|:  :.|..| ...||||.|||||.:.||||:.|::.|||
Zfish    81 QFNLMASEMIALNRSLPDVRLEGCKTK--VYPDDL-PRTSVVIVFHNEAWTTLLRTVHSVIDRSP 142

  Fly   139 EDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGR 203
            ...|.|::||||.|:||.     |||.:.. :..:..:.:..:|.::|.|||.:|.:|||:::|:
Zfish   143 RHLLEEIVLVDDASERDF-----LKRQLEH-YVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQ 201

  Fly   204 YVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWL 268
            .:.|||:|||...|||||||.|:.|:....|.|::|.|...|..|..|:::..|||:|.|:|.|.
Zfish   202 VITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWY 266

  Fly   269 ---KRQLTNQE-SLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQ 329
               :|::..:: ...:|.::|..|||:..:.|::|.::|:::..:.|||||::|::.::|.|||.
Zfish   267 PVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGT 331

  Fly   330 IEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRI 394
            :|||.||.:||:||:...:.||..:.:.::       .|::.:||.|:||:||.||.:.|...::
Zfish   332 LEIVTCSHVGHVFRKATPYTFPGGTGQIIN-------KNNRRLAEVWMDEFKNFFYIISPGVTKV 389

  Fly   395 PLDHTYDELQ---RMRKERRCHPFEWYLRHVSPELRM--HFDELSATGTLRN--EDRCVH--ARQ 450
                .|.::.   .:|:..:|.||.|||.:|.|:.::  |:..|   |.:||  .::|:.  ||:
Zfish   390 ----DYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHYYSL---GEIRNVETNQCLDNMARK 447

  Fly   451 KDSQPILASCYLSDITQWSMLRQSGQLSTHRELCLAVG-FGMRIALEPCGRNETVRRSQRW---- 510
            ::.:..:.:|:.....|......:.::.|. :|||.|. ....:.:..|   ..::.:|.|
Zfish   448 ENEKVGIFNCHGMGGNQVFSYTANKEIRTD-DLCLDVSKLNGPVMMLKC---HHLKGNQLWEYDP 508

  Fly   511 VRLGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSFQFAL 552
            |:|.  |:|..|:.|||...:|..::.:.|..:.::|.|:.|
Zfish   509 VKLS--LVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLL 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	117/315 (37%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	26/121 (21%)
galnt1	XP_009290644.1	pp-GalNAc-T	117..417	CDD:133004	117/316 (37%)
		RICIN	430..548	CDD:238092	28/123 (23%)
		Ricin_B_lectin	430..546	CDD:279046	27/121 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820