Protein Alignment CG10000 and GALNT10

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_938080.1
• Gene: GALNT10 / 55568
• HGNCID: 19873
• Length: 603
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 163/511 - (31%)
• Similarity: 266/511 - (52%)
• Gaps: 69/511 - (13%)

  Fly    75 YNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPE 139
            :||::|:.:.|.|.||..||.:|.::..:...|   |.|::|.||||..|.||||:.|:|:|||.
Human   113 FNIYVSDKISLNRSLPDIRHPNCNSKRYLETLP---NTSIIIPFHNEGWSSLLRTVHSVLNRSPP 174

  Fly   140 DYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRY 204
            :.:.|::||||.|.|: .|...|:.:| .:|.|     :..||.::|.|||.:|..|||:|:|..
Human   175 ELVAEIVLVDDFSDRE-HLKKPLEDYM-ALFPS-----VRILRTKKREGLIRTRMLGASVATGDV 232

  Fly   205 VLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYR-KGNELLKGGFDWSLHFHWL 268
            :.|||||||.|..||.|||:|:|.|....|.|::|.||.....|. :..:.::|.|||.:::
Human   233 ITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYY--- 294

  Fly   269 KR-----QLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGG 328
            ||     :|...:..: |::||..|||:..:.|:||.:||.::|.|:|||||..|::.|:|:|||
Human   295 KRIPIPPELQKADPSD-PFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGG 358

  Fly   329 QIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARR 393
            ::|.:||||:|||:|:     :.|..    .||..:...|.|.:||.|:|||....|..||..|.
Human   359 RMEDIPCSRVGHIYRK-----YVPYK----VPAGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRH 414

  Fly   394 IPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHFDEL----SATGTLRNE------------ 442
            :.......: :::|....|..|:|::..::.:|...:..:    :|.|.:||.
Human   415 LSAGDVAVQ-KKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGA 478

  Fly   443 -------DRCVHARQK---DSQPILASCYLSDITQWSMLRQSGQLSTHRELCL-AVGFGMRIALE 496
                   :.||..|.:   ::..:....:..||       :.|.....::.|. |:.....:.|.
Human   479 LGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDI-------RPGDPQHTKKFCFDAISHTSPVTLY 536

  Fly   497 PCGRNETVRRSQRW-VRLGTHLLHAESHLCLDNPLKD-RLEMSTCRSHAVSQSFQF 550
            .|   .:::.:|.| .|....|.|..|..|:|....| |:.|:||...:::|.:.|
Human   537 DC---HSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLF 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	121/314 (39%)
		Ricin_B_lectin	435..548	CDD:279046	28/137 (20%)
GALNT10	NP_938080.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..59
		Catalytic subdomain A	144..253		55/118 (47%)
		GT2	145..449	CDD:224137	124/327 (38%)
		pp-GalNAc-T	148..443	CDD:133004	121/315 (38%)
		Catalytic subdomain B	311..373		32/61 (52%)
		Flexible loop	373..384		4/19 (21%)
		Ricin_B_lectin	459..587	CDD:279046	28/137 (20%)
		RICIN	461..589	CDD:238092	27/137 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810