DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt13

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_031748551.1	Gene:	galnt13 / 550031	XenbaseID:	XB-GENE-1012445	Length:	571	Species:	Xenopus tropicalis

Alignment Length:	557	Identity:	175/557 - (31%)
Similarity:	287/557 - (51%)	Gaps:	81/557 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 HCSFYIIAFLICQLFFLVIFIRNDDASSANELLSFMNESEESDHLD------WRVFISHTPE--- 67
            :|...:...|:..|  |.:|:          ||.|...::..|..|      .|..||.|||
Frog     6 YCKVVLATSLVWVL--LDVFL----------LLYFSECNKCDDRKDRSLLPALRAVISRTPEGPG 58

  Fly    68 --------TSED---------FYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVV 115
                    ..:|         ..|:|:..|:.:.|.|.||..|...|.|:  :.|..| .|.|:|
Frog    59 ELGKAVIIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTK--VYPDEL-PNTSIV 120

  Fly   116 ISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTF 180
            |.|||||.|.||||:.|:::|||...:.|:|||||.|:||. |...|:.::     ....:.:..
Frog   121 IVFHNEAWSTLLRTVHSVINRSPHRLISEIILVDDSSERDF-LKSPLENYV-----KHLEVPVKI 179

  Fly   181 LRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTT 245
            ||.::|.|||.:|.|||::|.|:.:.|||:|||...|||||||.|:..:....|.|::|.|...|
Frog   180 LRMEQRSGLIRARLRGANVAKGQIITFLDAHCECTIGWLEPLLARIKEDRKTVVCPIIDVISDDT 244

  Fly   246 LSYRKGNELLKGGFDWSLHFHWL---KRQLTNQE-SLEMPYQSPAFAGGVLMMSREWFLKLGSFN 306
            ..|..|:::..|||:|.|:|.|.   :|::..:: ...:|.::|..|||:..:.:.:|.:||:::
Frog   245 FEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKTYFEELGTYD 309

  Fly   307 PYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKI 371
            ..:.|||||::|::.::|.|||.:|||.||.:||:||:...:.||..:...::       .|::.
Frog   310 SGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVIN-------KNNRR 367

  Fly   372 IAESWLDEYKNMFYALRPAARRIPLDH-TYDELQRMRKERRCHPFEWYLRHVSPEL---RMHFDE 432
            :||.|:|::|:.||.:.|..  :.:|: ...|.:.:|:..:|:||.|||..|.|:.   |.:|
Frog   368 LAEVWMDDFKDFFYIISPGV--VKVDYGDVSERKALRENLKCNPFSWYLETVYPDSQIPRRYF-- 428

  Fly   433 LSATGTLRN--EDRCVH--ARQKDSQPILASCYLSDITQWSMLRQSGQLSTHRELCLAVG--FGM 491
              :.|.:||  .::|:.  .|:::.:..:.:|:.....|........::.|. :|||.|.  .|.
Frog   429 --SLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTD-DLCLDVSRLNGP 490

  Fly   492 RIALEPCGRNETVRRSQRW-VRLGTH-LLHAESHLCL 526
            .|.|: |   ..:|.:|.| ....|| .||..:..||
Frog   491 VIMLK-C---HHMRGNQLWEYDAETHTFLHIITQSCL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	116/313 (37%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	25/100 (25%)
galnt13	XP_031748551.1	pp-GalNAc-T	118..418	CDD:133004	116/314 (37%)
galnt13	XP_031748551.1	Ricin_B_lectin	431..548	CDD:395527	25/98 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920