DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and Galnt4

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001020224.2	Gene:	Galnt4 / 500826	RGDID:	1564589	Length:	578	Species:	Rattus norvegicus

Alignment Length:	508	Identity:	166/508 - (32%)
Similarity:	260/508 - (51%)	Gaps:	61/508 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 YQYNIHLSNALGLIRKLPVTRHHSCTTRN---SILPAPLEANVSVVISFHNEARSMLLRTIVSLL 134
            |..||:||:.:.|.|.:...|.:.|..:.   ..||     ..||:|:|:|||.|.|||||.|:|
  Rat   100 YAINIYLSDRISLHRHIEDKRMYECKAKKFHYRSLP-----TTSVIIAFYNEAWSTLLRTIHSVL 159

  Fly   135 SRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASL 199
            ..||...|.|:|||||.|.| :.|...|:.::..:  .|.||    :|..:|.||:.:|..||:.
  Rat   160 ETSPAVLLKEIILVDDLSDR-IYLKAQLEAYISNL--DRVRL----IRTNKREGLVRARLIGATF 217

  Fly   200 ASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLS-YRKGNELLKGGFDWSL 263
            |:|..:.|||.|||.|.|||||||||::.:....|.|::|.||..|.. |.:..|.:.|||||.|
  Rat   218 ATGDVLTFLDCHCECNTGWLEPLLERISRDETAIVCPVIDTIDWNTFEFYMQTGEPMIGGFDWRL 282

  Fly   264 HFHW---LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWL 325
            .|.|   .|.:...:.|...|.:||..|||:..:|:::|..||:::..:::||||::||:.::|.
  Rat   283 TFQWHSVPKHERDRRTSRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQ 347

  Fly   326 CGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPA 390
            |||::||.|||.:||:|.:|..:            |:..:|.|:...||.|:|:||..||...|.
  Rat   348 CGGKLEIHPCSHVGHVFPKRAPY------------ARPNFLQNTARAAEVWMDDYKEHFYNRNPP 400

  Fly   391 ARRIPLDHTYDELQR---MRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN---EDRCVHAR 449
            ||:    .||.::..   :|:..:|..|:|||::|...|.:..|.....|.:|:   ...|:...
  Rat   401 ARK----ETYGDISERKLLRERLQCKSFDWYLKNVFSNLHVPEDRPGWHGAIRSMGISSECLDYN 461

  Fly   450 QKDSQPI-----LASCYLSDITQWSMLRQSGQL--STHRELCLAVGFGM-RIALEPC---GRNET 503
            ..|:.|.     |..|:.....|:.....:.::  ::..|||..|.... .:.::.|   |....
  Rat   462 APDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPQQKDYVGMQNCPKDGLPIP 526

  Fly   504 VRRSQRWVRLGTHLLHAESHLCL------DNPLKDRLEMSTCRSHAVSQSFQF 550
            |.....:...|| :.|..:.|||      |.  :..::|.||.:...:|.::|
  Rat   527 VNIIWHFKEDGT-IFHPHTRLCLSAYRTADG--RPSVQMKTCDALDKNQIWRF 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	125/315 (40%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	26/132 (20%)
Galnt4	NP_001020224.2	WcaA	133..430	CDD:223539	127/324 (39%)
		pp-GalNAc-T	138..432	CDD:133004	125/316 (40%)
		RICIN	446..576	CDD:238092	26/132 (20%)
		Ricin_B_lectin	446..574	CDD:279046	26/130 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010