DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and Pgant35A

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	169/500 - (33%)
Similarity:	264/500 - (52%)	Gaps:	71/500 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 YQYNIHLSNALGLIRKLPVTRHHSC----TTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSL 133
            :.:|..:||.:||.|.:|.|||..|    ||....||     ..|:|:.|:||.:..|:|:|.::
  Fly   112 HAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLP-----QASIVMCFYNEHKMTLMRSIKTV 171

  Fly   134 LSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRL-GLTFLRNQERMGLIWSRNRGA 197
            |.|:|...|.|:|||||.|.     |.:|:..:.|...:|.:. .|.:::|::|.|||.||..||
  Fly   172 LERTPSYLLREIILVDDHSD-----LPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGA 231

  Fly   198 SLASGRYVLFLDSHCEVNEGWLEPLLERL-ALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDW 261
            ..|.|..::|||||.|||:.||||||..: :.|..||| |::|.|:..|..|.. :.|::|||:|
  Fly   232 REAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAV-PVIDLINADTFEYTP-SPLVRGGFNW 294

  Fly   262 SLHFHW---LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKL 323
            .|||.|   .:..|...|....|::||..|||:..::|::|..||.::..:.|||||:||::.:.
  Fly   295 GLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRA 359

  Fly   324 WLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALR 388
            |.|||.|:||||||:|||||:|..:..|..::        |.|.||..:|..|:|:||:  |.|:
  Fly   360 WQCGGAIKIVPCSRVGHIFRKRRPYTSPDGAN--------TMLKNSLRLAHVWMDQYKD--YYLK 414

  Fly   389 PAARRIPLDHTYDELQ---RMRKERRCHPFEWYLRHVSPELRMHFDE--LSATGTLRNEDRCVHA 448
              ..::|..:.|.::.   ::|:..:|..|.|||::|.|||.:..:|  .||...:...   .|:
  Fly   415 --HEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQP---WHS 474

  Fly   449 RQKDSQPILASCYLSDITQWSMLRQSGQLSTHRELCLAV------GF---GMRIALEPCGRNETV 504
            |:::        |:...    .||.:|     .|||.||      ||   |..:.|:.|.|..
  Fly   475 RKRN--------YVDTF----QLRLTG-----TELCAAVVAPKVKGFWKKGSSLQLQTCRRTP-- 520

  Fly   505 RRSQRWVRLGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSFQ 549
              :|.|.......:..:..|||:.....::.::.|......|.::
  Fly   521 --NQLWYETEKAEIVLDKLLCLEASGDAQVTVNKCHEMLGDQQWR 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	123/316 (39%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	25/121 (21%)
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	123/317 (39%)
		RICIN	489..610	CDD:214672	19/83 (23%)
		RICIN	490..609	CDD:238092	18/77 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920