DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and CG7579

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	154/518 - (29%)
Similarity:	243/518 - (46%)	Gaps:	61/518 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ESDHLDWRVFISHTPETSEDFYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVI 116
            |:|.:|        .:...:.||||..||..:.|.|.|...|...|...|  ..:.....||:||
  Fly     3 ETDLVD--------AQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKIN--YSSEKTVTVSIVI 57

  Fly   117 SFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTF- 180
            :...|....|||.|.|:::::....|.|::||.|| ..|:.|:..:          .::|.:..
  Fly    58 AIQQEHPHTLLRGIYSVITQTSPYLLKEIVLVHDG-HPDLDLIRHI----------HHKLPIVIQ 111

  Fly   181 LRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTT 245
            |..:...|:|.:|..||.:|:|..::||:.|.||..|||.||||.:.||......|::|.|...:
  Fly   112 LEMESSKGIIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRES 176

  Fly   246 LSYRKGNELLKGGFDWSLHFHWLKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLK 310
            .:|||..|..:..|||.|...:|.....:..||..||.|....|.|..:.|:||..||.::..|:
  Fly   177 FAYRKLVEPEQLAFDWQLDHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLR 241

  Fly   311 IWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLH---NSKII 372
            .:||:::||::|:|.|||.|..|||||:|.|::|       .:.:.|::|.:...|.   |.|.:
  Fly   242 DYGGDALELSLKVWQCGGLILAVPCSRVGIIYKR-------DELEAQMAPNRNPSLQVQKNFKRV 299

  Fly   373 AESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSAT- 436
            .:.||||||..||...|..|.:..: :.|:.:.:|:...|..||||...|:|::|.||.....|
  Fly   300 VDVWLDEYKLHFYRYNPKLRNLTAE-SLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTN 363

  Fly   437 ---GTLR---NEDRCVHARQKDSQPILASCYLSDITQWSMLRQSGQLSTHRELCLAVGFGMRIAL 495
               |.:.   ....|:..  |...|::..|:.::...|::..:. ||. |..:||.|.:...:..
  Fly   364 YPIGKIMPFVAPHFCLSI--KGGFPVIRKCHSTNFEDWTLTSRC-QLK-HGNMCLDVDYKNNVRA 424

  Fly   496 EPCGRNETVRRSQR-WVRLGTHLLHAES------HLCLDNPL-KDRLEMSTCRSHAVSQSFQF 550
            ..|    |.:.|:. |     |..:..|      :.||...: |..|.:|.|.|....|.:.|
  Fly   425 TKC----TKKLSKNPW-----HYNYQHSSFVSNGNKCLQIDVNKVGLILSACDSDVTEQRWMF 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	105/312 (34%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	27/127 (21%)
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	101/302 (33%)
		pp-GalNAc-T	54..349	CDD:133004	105/313 (34%)
		RICIN	367..478	CDD:238092	26/123 (21%)
		Ricin_B_lectin	373..476	CDD:279046	25/115 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910