Protein Alignment CG10000 and GALNT18

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_940918.2
• Gene: GALNT18 / 374378
• HGNCID: 30488
• Length: 607
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 170/605 - (28%)
• Similarity: 264/605 - (43%)
• Gaps: 110/605 - (18%)

  Fly    21 LICQL-------FFLVIFIRNDDASSANELLSFMNES----EESDHLDWRVFISH------TPET 68
            :||.|       :...:::|..:.:...:|.....::    |..|||: .|...|      .||.
Human    23 IICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLE-NVIKQHIQEAPAKPEE 86

  Fly    69 SE-----------------------------DFYQYNIHLSNALGLIRKLPVTRHHSCTTRNSIL 104
            :|                             .:|.||.:||:.|.|.|.||..|...|  ||...
Human    87 AEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGC--RNLSF 149

  Fly   105 PAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGV 169
            |..| ..||:|..|.|||.|:|||:|.|.:.|:|...|.|:|||||.|..: .|.:.|..::..|
Human   150 PDSL-PEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNE-ELKEKLTEYVDKV 212

  Fly   170 FGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAV 234
             .|:....:..:|:.::.|||.||..|...|:...|...|:|.|.|.||.||:|.|:..|....:
Human   213 -NSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRII 276

  Fly   235 SPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWLK--RQLTNQESLEMPYQSPAFAGGVLMMSRE 297
            ||..|.|........: ..|...||||.|...:|.  :.....|:...|.:|||.. |..::.|:
Human   277 SPSFDNIKYDNFEIEE-YPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALI-GCFIVDRQ 339

  Fly   298 WFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQ 362
            :|.::|..:..::::|||::||.|::|.|||.:|::|||||.||.|....:            .:
Human   340 YFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPY------------TE 392

  Fly   363 ETYLH---NSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDEL------QRMRKERRCHPFEWY 418
            :...|   |:..:||.|:||:|:..|    .|..||.:.:..::      :.:||:.:|..|.||
Human   393 DLTAHVRRNALRVAEVWMDEFKSHVY----MAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWY 453

  Fly   419 LRHVSPELRMHFDELSATGTLRNE---DRCV-HARQKDSQPILASCYLSDITQWSMLRQSGQ--- 476
            |..|.||:||:.| :.|.|.|:|.   |.|: .....::.||:..|:  .:|..::...|.|
Human   454 LVSVYPEMRMYSD-IIAYGVLQNSLKTDLCLDQGPDTENVPIMYICH--GMTPQNVYYTSSQQIH 515

  Fly   477 -------LSTHRELCLAVGFGMRIALEPCGRNETVRRSQRW-VRLGTHLLHAESHLCLDNPLKDR 533
                   :......|| |....|..|..|...:..|....| ...|..:.:.:|..||:......
Human   516 VGILSPTVDDDDNRCL-VDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSD 579

  Fly   534 LEMSTCRSHAVSQSFQFALE 553
            ||.          .||..|:
Human   580 LEF----------GFQLVLQ 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	104/319 (33%)
		Ricin_B_lectin	435..548	CDD:279046	26/127 (20%)
GALNT18	NP_940918.2	Catalytic subdomain A	153..267		46/116 (40%)
		pp-GalNAc-T	157..458	CDD:133004	104/320 (33%)
		Catalytic subdomain B	324..385		26/61 (43%)
		RICIN	471..598	CDD:238092	28/132 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810