Protein Alignment CG10000 and Galntl6

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001129228.1
• Gene: Galntl6 / 361142
• RGDID: 1564773
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 191/615 - (31%)
• Similarity: 302/615 - (49%)
• Gaps: 122/615 - (19%)

  Fly    20 FLICQLFFLV--IFIRNDDASSANELLSFMNESEESDH---------------------LDWRVF 61
            ||...|.|.|  ||:.|....|..:....|..:|.::|                     .||..:
  Rat     8 FLQMTLLFTVALIFLPNIGLWSLYKDKHLMKSAEPAEHQTFPLGLGDGQFYSWTDGLRRKDWHDY 72

  Fly    62 IS------------H---TPETSEDF----YQ---YNIHLSNALGLIRKLPVTRHHSCTTRNSIL 104
            :|            |   .|.|.||.    |:   :||.:||.:.|.|.||..||.:|..:..:.
  Rat    73 VSIQKDALRSGKGEHGKPYPLTEEDHDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLE 137

  Fly   105 PAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGV 169
            ..|   |.|::|.||||..:.|||||.|:::|:||..:.|:|||||.|.|: .|.|.|:.:|
  Rat   138 RLP---NTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDRE-HLKDKLEDYM--- 195

  Fly   170 FGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAV 234
              :|:.: :..:|.::|.|||.:|..|||:|.|..:.|||||||||..||.|||.::|||....|
  Rat   196 --ARFPI-VRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIV 257

  Fly   235 SPLLDPIDPTTLSYR-KGNELLKGGFDWSLHFHWLKR-----QLTNQESLEMPYQSPAFAGGVLM 293
            .|::|.||.:...|. :..:.::|.|||.:::   ||     :|...:..| |::||..|||:..
  Rat   258 CPMIDVIDHSHFGYEAQAGDAMRGAFDWEMYY---KRIPIPPELQRADPSE-PFESPVMAGGLFA 318

  Fly   294 MSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQL 358
            :.|:||.:||.::|.|:|||||..|::.|:|:|||::..|||||:|||:|:     :.|..
  Rat   319 VDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRK-----YVPYK---- 374

  Fly   359 SPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVS 423
            .|:..:...|.|.:||:|:||:....|..||..|.:.......: :.:||..:|..|:|::..|:
  Rat   375 VPSGTSLARNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQ-KELRKRLKCKDFKWFMAAVA 438

  Fly   424 PELRMHFDEL----SATGTLRN--EDRCVHARQ-------------KDSQPILASCYLSDITQWS 469
            .::..::..:    :|.|.:||  .:.||.::.             ||.         |:.| ||
  Rat   439 WDVPKYYPPVEPLPAAWGEIRNVAANLCVDSKHGAMGTELRLDICVKDG---------SERT-WS 493

  Fly   470 M-----------LRQSGQLSTHRELCL-AVGFGMRIALEPCGRNETVRRSQRW-VRLGTHLLHAE 521
            .           :|....|.| |:.|| |:.....:.|..|   ..::.:|.| .|....|.|..
  Rat   494 HEQLFTFGWREDIRPGEPLHT-RKFCLDAISHSSPVTLYDC---HGMKGNQLWGYREDRTLFHPV 554

  Fly   522 SHLCLD-NPLKDRLEMSTCRSHAVSQSFQF 550
            |:.|:| ||.:.::.|:.|...:.:|.:.|
  Rat   555 SNSCMDCNPAEKKVFMARCDPLSETQQWMF 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	121/314 (39%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	34/150 (23%)
Galntl6	NP_001129228.1	pp-GalNAc-T	143..438	CDD:133004	121/315 (38%)
		beta-trefoil_Ricin_GALNTL6	449..594	CDD:467355	35/150 (23%)