DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and Galnt13

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_036018146.1	Gene:	Galnt13 / 271786	MGIID:	2139447	Length:	613	Species:	Mus musculus

Alignment Length:	542	Identity:	165/542 - (30%)
Similarity:	274/542 - (50%)	Gaps:	101/542 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QYNIHLSNALGLIRKLPVTRHH------------------------------------SCTT--- 99
            |:|:..|:.:.|.|.||..|..                                    .|.|
Mouse    82 QFNLMASDLIALNRSLPDVRLEGQYCCGRCEELQTMQQERYARVYISTNFCSSILFWLKCNTELR 146

  Fly   100 -RNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRD---VTLLD 160
             :..:.|..| .|.||||.|||||.|.||||:.|:::|||...|.|:|||||.|:||   :||.:
Mouse   147 CKTKVYPDEL-PNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLEN 210

  Fly   161 DLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLER 225
            .:|         ...:.:..:|.:||.|||.:|.|||:.:.|:.:.|||:|||...|||||||.|
Mouse   211 YVK---------TLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLAR 266

  Fly   226 LALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWL---KRQLTNQE-SLEMPYQSPA 286
            :..:....|.|::|.|...|..|..|:::..|||:|.|:|.|.   :|::..:: ...:|.::|.
Mouse   267 IKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPT 331

  Fly   287 FAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFP 351
            .|||:..:.|.:|.::|:::..:.|||||::|::.::|.|||.:|||.||.:||:||:...:.||
Mouse   332 MAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFP 396

  Fly   352 PQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDEL---QRMRKERRCH 413
            ..:...::       .|::.:||.|:||:|:.||.:.|...::    .|.::   :.:|:..:|.
Mouse   397 GGTGHVIN-------KNNRRLAEVWMDEFKDFFYIISPGVVKV----DYGDVSVRKTLRENLKCK 450

  Fly   414 PFEWYLRHVSPEL---RMHFDELSATGTLRN--EDRCVH--ARQKDSQPILASCYLSDITQWSML 471
            ||.|||.::.|:.   |.::    :.|.:||  .::|:.  .|:::.:..:.:|:.....|....
Mouse   451 PFSWYLENIYPDSQIPRRYY----SLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSY 511

  Fly   472 RQSGQLSTHRELCLAVG--FGMRIALEPCGRNETVRRSQRW-VRLGTH-LLHAESHLCL-----D 527
            ....::.|. :|||.|.  .|..|.|: |   ..:|.:|.| ....|| |:|..:..||     :
Mouse   512 TADKEIRTD-DLCLDVSRLSGPVIMLK-C---HHMRGNQLWEYDAETHTLVHIITQSCLSMGKGE 571

  Fly   528 NPLKDRLEMSTCRSHAVSQSFQ 549
            :..:| |.|.||.    ..:||
Mouse   572 DGSQD-LSMETCN----DSTFQ 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	118/318 (37%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	30/125 (24%)
Galnt13	XP_036018146.1	pp-GalNAc-T	160..460	CDD:133004	118/319 (37%)
Galnt13	XP_036018146.1	Ricin_B_lectin	473..590	CDD:395527	32/126 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820