DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and Pgant4

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	586	Identity:	173/586 - (29%)
Similarity:	281/586 - (47%)	Gaps:	102/586 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RND--DASSANELLSFMNESEESDHLDWRVFIS-------------------HTPETSE---DFY 73
            ||.  |...:::|..|.....:.:..||..:.:                   ..|:..:   :.|
  Fly    77 RNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHY 141

  Fly    74 Q---YNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLS 135
            :   :|..:|:.:.:.|.:|..|..:|.||..:...|   |:||:..|.||..:.|||:|.|:::
  Fly   142 EMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLP---NISVIFIFFNEHFNTLLRSIYSVIN 203

  Fly   136 RSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLA 200
            |:|.:.|.:::||||||:.||     ||:.:.......:...:|.:||.||.|||.:|..||.:|
  Fly   204 RTPPELLKQIVLVDDGSEWDV-----LKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVA 263

  Fly   201 SGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGN-ELLKGGFDWSLH 264
            .|:.::|.|||.|||..||.||:|.:|:|..::..|::|.|.....||..|| :..:|||||.:
  Fly   264 VGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKM- 327

  Fly   265 FHWLKRQL--TNQESLE--MPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWL 325
               |.:||  ..:::|:  |||:||...||:..::.::|..||.::..|.|||||..||:.|:|:
  Fly   328 ---LYKQLPVLPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWM 389

  Fly   326 CGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPA 390
            |||.:..|||||:.||||       .|...|...........|.|.:||.|:||||...|...|
  Fly   390 CGGMLLDVPCSRVAHIFR-------GPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDP- 446

  Fly   391 ARRIPLDHTYDEL-------QRMRKER-RCHPFEWYLRHVSPELRMHFDELS----ATGTLRNED 443
                   .|||.|       ||..:|| :|..|.|::..|:|:..:.|..:.    |.|.::|..
  Fly   447 -------KTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVA 504

  Fly   444 R---CVHARQKDSQPILASCYLSDITQWSMLRQSGQLSTHREL--------CLAVGFG---MRIA 494
            .   |:....|.::..:.....:|........|..:||..|:|        ||.|..|   ..:.
  Fly   505 NPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVW 569

  Fly   495 LEPC---GRNE---TVRRSQRWVRLGTHLLHAESH-LCLDNPLKD---RLEMSTCRSHAVSQSFQ 549
            :..|   |.|:   ..|::||       |:|.|:: .||:..:::   ::..::|.:....|.::
  Fly   570 MWSCHSQGGNQFWYYDRQTQR-------LVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWE 627

  Fly   550 F 550
            |
  Fly   628 F 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	122/321 (38%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	28/136 (21%)
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	98/245 (40%)
		pp-GalNAc-T	181..480	CDD:133004	122/322 (38%)
		Ricin_B_lectin	496..626	CDD:279046	28/136 (21%)
		RICIN	498..628	CDD:238092	27/136 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910