Protein Alignment CG10000 and GALNT1

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001371367.1
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 159/497 - (31%)
• Similarity: 279/497 - (56%)
• Gaps: 47/497 - (9%)

  Fly    74 QYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSP 138
            |:|:..|..:.|.|.||..|...|.|:  :.|..| ...||||.|||||.|.||||:.|:::|||
Human    83 QFNLMASEMIALNRSLPDVRLEGCKTK--VYPDNL-PTTSVVIVFHNEAWSTLLRTVHSVINRSP 144

  Fly   139 EDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGR 203
            ...:.|::||||.|:||.     |||.:.. :..:.::.:..:|.::|.|||.:|.:||:::.|:
Human   145 RHMIEEIVLVDDASERDF-----LKRPLES-YVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQ 203

  Fly   204 YVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWL 268
            .:.|||:|||...|||||||.|:..:....|.|::|.|...|..|..|:::..|||:|.|:|.|.
Human   204 VITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWY 268

  Fly   269 ---KRQLTNQE-SLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQ 329
               :|::..:: ...:|.::|..|||:..:.|::|.::|:::..:.|||||::|::.::|.|||.
Human   269 PVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGT 333

  Fly   330 IEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRI 394
            :|||.||.:||:||:...:.||..:.:.::       .|::.:||.|:||:||.||.:.|...::
Human   334 LEIVTCSHVGHVFRKATPYTFPGGTGQIIN-------KNNRRLAEVWMDEFKNFFYIISPGVTKV 391

  Fly   395 PLDHTYDELQR---MRKERRCHPFEWYLRHVSPELRM--HFDELSATGTLRN--EDRCVH--ARQ 450
                .|.::..   :|.:.:|.||.|||.::.|:.::  |:..|   |.:||  .::|:.  ||:
Human   392 ----DYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSL---GEIRNVETNQCLDNMARK 449

  Fly   451 KDSQPILASCYLSDITQWSMLRQSGQLSTHRELCLAVG-FGMRIALEPCGRNETVRRSQRW---- 510
            ::.:..:.:|:.....|......:.::.|. :|||.|. ....:.:..|   ..::.:|.|
Human   450 ENEKVGIFNCHGMGGNQVFSYTANKEIRTD-DLCLDVSKLNGPVTMLKC---HHLKGNQLWEYDP 510

  Fly   511 VRLGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSFQFAL 552
            |:|  .|.|..|:.|||...::..::.:.|....|:|.|:.|
Human   511 VKL--TLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	115/315 (37%)
		Ricin_B_lectin	435..548	CDD:279046	26/121 (21%)
GALNT1	NP_001371367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65
		Catalytic subdomain A	115..225		52/116 (45%)
		pp-GalNAc-T	119..419	CDD:133004	115/316 (36%)
		Catalytic subdomain B	285..347		25/61 (41%)
		Ricin_B_lectin	432..548	CDD:395527	27/121 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820