Protein Alignment CG10000 and Galnt18

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_776100.2
• Gene: Galnt18 / 233733
• MGIID: 2446239
• Length: 622
• Species: Mus musculus
• Alignment Length: 620
• Identity: 170/620 - (27%)
• Similarity: 266/620 - (42%)
• Gaps: 125/620 - (20%)

  Fly    21 LICQL-------FFLVIFIRNDDASSANELLSFMNES----EESDHLDWRVFISH------TPET 68
            :||.|       :...:::|..:.....:|.....::    |..|||: .|...|      .||.
Mouse    23 IICLLYVGWVTNYIASVYVRGQEPVPDKKLEEDKGDTLKIIERLDHLE-NVIKQHIQEAPAKPEE 86

  Fly    69 SE-----------------------------DFYQYNIHLSNALGLIRKLPVTRHHSCTTRNSIL 104
            :|                             .:|.||.:||:.|.|.|.||..|...|  ||...
Mouse    87 AEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGC--RNLSF 149

  Fly   105 PAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGV 169
            |..| ..||:|..|.|||.|:|||:|.|.:.|:|...|.|:|||||.|..: .|.:.|..::..|
Mouse   150 PDSL-PEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNE-ELKEKLTEYVDKV 212

  Fly   170 FGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAV 234
            .|.:... :..:|:.::.|||.||..|...|:...|...|:|.|.|.||.||:|.|:..|....:
Mouse   213 NGQKPGF-IKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRII 276

  Fly   235 SPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHWLK--RQLTNQESLEMPYQSPAFAGGVLMMSRE 297
            ||..|.|........: ..|...||||.|...:|.  :.....|:...|.:|||.. |..::.|:
Mouse   277 SPSFDNIKYDNFEIEE-YPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALI-GCFIVDRQ 339

  Fly   298 WFLKLGSFNPYLKIWGGESIELAIK---------------LWLCGGQIEIVPCSRIGHIFRRRHA 347
            :|.::|..:..::::|||::||.|:               :|.|||.:|::|||||.||.|....
Mouse   340 YFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIERAHKP 404

  Fly   348 FDFPPQSDRQLSPAQETYLH---NSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDEL------ 403
            :            .::...|   |:..:||.|:||:|:..|    .|..||.:.:..::
Mouse   405 Y------------TEDLTAHVRRNALRVAEVWMDEFKSHVY----MAWNIPQEDSGIDIGDITAR 453

  Fly   404 QRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNE---DRCV-HARQKDSQPILASCYLSD 464
            :.:||:.:|..|.|||..|.||:||:.| :.|.|.|:|.   |.|: .....::.||:..|:  .
Mouse   454 KALRKQLQCKTFRWYLVSVYPEMRMYSD-IIAYGVLQNSLKTDLCLDQGPDTENVPIVYICH--G 515

  Fly   465 ITQWSMLRQSGQ----------LSTHRELCLAVGFGMRIALEPCGRNETVRRSQRW-VRLGTHLL 518
            :|..::...|.|          :......|| |....|..|..|...:..|....| ...|..:.
Mouse   516 MTPQNVYYTSSQQIHVGILSPTVDDDDNRCL-VDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQ 579

  Fly   519 HAESHLCLDNPLKDRLEMSTCRSHAVSQSFQFALE 553
            :.:|..||:  |::..:|..        .||..|:
Mouse   580 NRKSKRCLE--LQENSDMEF--------GFQLVLQ 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	104/334 (31%)
		Ricin_B_lectin	435..548	CDD:279046	26/127 (20%)
Galnt18	NP_776100.2	Catalytic subdomain A	153..267		46/116 (40%)
		pp-GalNAc-T	157..473	CDD:133004	104/335 (31%)
		Catalytic subdomain B	324..400		26/76 (34%)
		Ricin_B_lectin	484..611	CDD:279046	29/134 (22%)
		RICIN	486..613	CDD:238092	28/132 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900