Protein Alignment CG10000 and Galnt17

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_660253.2
• Gene: Galnt17 / 212996
• MGIID: 2137594
• Length: 598
• Species: Mus musculus
• Alignment Length: 535
• Identity: 143/535 - (26%)
• Similarity: 227/535 - (42%)
• Gaps: 130/535 - (24%)

  Fly    73 YQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRS 137
            |.||.:||..:.|.|.:|..|...|.........|   .:|::..|.|||.|::||::.|.::.:
Mouse   118 YGYNSYLSEKISLDRSIPDYRPTKCKELKYSKELP---QISIIFIFVNEALSVILRSVHSAVNHT 179

  Fly   138 PEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASG 202
            |...|.|:|||||.|..     ::||..:......||...:..:|||:|.|||.:|..|...|:|
Mouse   180 PTHLLKEIILVDDNSDE-----EELKAPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKAATG 239

  Fly   203 RYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHW 267
            :...|.|:|.|...||.||:|.|:..|....:.|.:|.|.......:: .|....|:.|.|...:
Mouse   240 QVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQR-YENSAHGYSWELWCMY 303

  Fly   268 LK--RQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQI 330
            :.  :...:.....:|.::||..|...:::|::|.::|..:|.:.::|||:|||.||:|||||.:
Mouse   304 ISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSM 368

  Fly   331 EIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKI----------IAESWLDEYKNMFY 385
            |::||||:.||.|::..:                   ||.|          :||.|:|:||:..|
Mouse   369 EVLPCSRVAHIERKKKPY-------------------NSNIGFYTKRNALRVAEVWMDDYKSHVY 414

  Fly   386 ALRPAARRIPLDH------TYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN--- 441
                .|..:||::      ...|.:.:||..:|..|:|||.||.||:| .::...|.|.|||
Mouse   415 ----IAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMR-RYNNTIAYGELRNNKA 474

  Fly   442 ------------------------------------------------EDRCVHARQKDSQPILA 458
                                                            :.||:....|...|.|.
Mouse   475 KDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLL 539

  Fly   459 SC---YLSDITQWSMLRQSGQLSTHRELCLAV---GF-GMRIALEPCGRNETVRRSQRWVRLGTH 516
            .|   ..|...:|:.::....::.....||.|   |. |:.:.|..|       ..|||
Mouse   540 DCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVENRGLAGIDLILRSC-------TGQRW------ 591

  Fly   517 LLHAESHLCLDNPLK 531
                    .:.||:|
Mouse   592 --------AIKNPIK 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	101/326 (31%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	26/158 (16%)
Galnt17	NP_660253.2	Catalytic subdomain A	151..262		43/118 (36%)
		pp-GalNAc-T	155..454	CDD:133004	102/327 (31%)
		Catalytic subdomain B	319..381		28/61 (46%)
		beta-trefoil_Ricin_GALNT17	457..598	CDD:467352	26/162 (16%)