DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10000 and gly-8

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001366981.1	Gene:	gly-8 / 176595	WormBaseID:	WBGene00001633	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	387	Identity:	125/387 - (32%)
Similarity:	211/387 - (54%)	Gaps:	33/387 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ESDHLDWRVFISHTPETSEDFYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVI 116
            ||...:|.:          ..:.::...|..||..|.:....|..|....    .....:.|||:
Worm    63 ESKKSEWGI----------KSFAFDALSSEKLGPNRNVGKQAHKLCEEEK----YDASYSTSVVV 113

  Fly   117 SFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFL 181
            ..||||.|.:||.|..::..:|:..|.|::|.:|.|:.|..|...|::: ..:.|...:  |...
Worm   114 IHHNEALSTILRMINGIIEFTPKSLLKEIVLYEDASEEDHVLTKHLEKF-AKIKGLEDK--LIIK 175

  Fly   182 RNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTL 246
            |::.|.|||.::...:.||:|..::|:||||||.|.||||||:.:..:....|.|::|.|:|.:.
Worm   176 RSEYRQGLIRAKVHASRLATGEVIVFMDSHCEVAERWLEPLLQPIKEDPKSIVLPVVDLINPVSF 240

  Fly   247 SYRKGNELLKGGFDWSLHFHWLK---RQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPY 308
            .| ..:.:.|.||||...|.|:.   ......|:...|:.|||..||:|.|.:|:|::||.::..
Worm   241 DY-SPSMVAKSGFDWGFTFKWIYLPWEYFETPENNVKPFNSPAMPGGLLAMRKEYFVELGEYDMG 304

  Fly   309 LKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIA 373
            ::|||.|:|||::|.|||||::.:.||||:||:||.|.     |.:.:   |..:|.|:|:..:|
Worm   305 MEIWGSENIELSLKAWLCGGRVVVAPCSRVGHVFRMRR-----PYTSK---PGMDTALYNAVRVA 361

  Fly   374 ESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVSPEL--RMHFDEL 433
            ::||.||::.|:|::|...::......:.:| ::...:|...:|::.:|.|||  ::| |||
Worm   362 KTWLGEYESKFFAVKPRGAKMVFGDLTEPMQ-VKDRLKCKDMKWFIENVYPELEPKVH-DEL 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	108/311 (35%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046
gly-8	NP_001366981.1	pp-GalNAc-T	110..410	CDD:133004	108/312 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820