Protein Alignment CG10000 and gly-9

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001022876.1
• Gene: gly-9 / 176557
• WormBaseID: WBGene00012934
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 611
• Identity: 180/611 - (29%)
• Similarity: 285/611 - (46%)
• Gaps: 106/611 - (17%)

  Fly     6 KYCGPR-HCSFYIIAFLICQLFFLVIFIRNDDASSANELLSFMNESEESDHL--DWRVFISHTPE 67
            :|..|| ..:|.|.|||....|.:|.:.|||...:..:.......:||...|  .|...:...|.
 Worm     3 RYIIPRKKGTFVIAAFLTVAFFCIVAYHRNDRRRTKFQFPDIEKYAEELVRLPETWNGELHQIPN 67

  Fly    68 -----------------TSEDF---------YQYNIHLSNALGLIRKLPVTRHHSCTTRN---SI 103
                             |.:|.         :..|:|.|:.:.|.|.:|..|..:|....   :.
 Worm    68 YTAPREGPGEKGKPVVLTGKDAELGQADMKKWFMNVHASDKISLDRDVPDPRIQACKDIKYDYAA 132

  Fly   104 LPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQR---DVTLLDDLKRW 165
            ||     ..||:|.|.:||.:.||||:.|:::|||.:.|.|:||:||.|:|   ...|.:.:||
 Worm   133 LP-----KTSVIIIFTDEAWTPLLRTVHSVINRSPPELLQEVILLDDNSKRQELQEPLDEHIKR- 191

  Fly   166 MGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNT 230
                ||.:.||    :|...|.|||.::..||..|.|..::|||||||.|.|||||:::|::...
 Worm   192 ----FGGKVRL----IRKHVRHGLIRAKLAGAREAVGDIIVFLDSHCEANHGWLEPIVQRISDER 248

  Fly   231 NLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHW--LKRQLTNQESLEMPY-QSPAFAGGVL 292
            ...|.|::|.|...||:|.....|..|||.|:|||.|  |..:...:.:....| :||..|||:|
 Worm   249 TAIVCPMIDSISDNTLAYHGDWSLSTGGFSWALHFTWEGLSEEEQKRRTKPTDYIRSPTMAGGLL 313

  Fly   293 MMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQ 357
            ..:||:|.::|.::..:.|||||::|::.:.|:|||.||.:|||.:|||||..|.::...:::.
 Worm   314 AANREYFFEVGGYDEEMDIWGGENLEISFRAWMCGGSIEFIPCSHVGHIFRAGHPYNMTGRNNN- 377

  Fly   358 LSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYD-----ELQRMRKERRCHPFEW 417
                ::.:..|||.:||.|:|:||.::|..|...|      |.|     ....:||...|.||:|
 Worm   378 ----KDVHGTNSKRLAEVWMDDYKRLYYMHREDLR------TKDVGDLTARHELRKRLNCKPFKW 432

  Fly   418 YLRHVSPELRMHFDELSA--------------TGTLRNEDR------CVHARQKDSQPILASCYL 462
            :|.:::....:..:::.|              |.||:.:::      ..|.:.|.|.|.|.|
 Worm   433 FLDNIAKGKFIMDEDVVAYGALHTVVSGTRMCTDTLQRDEKMSQLLGVFHCQGKGSSPQLMS--- 494

  Fly   463 SDITQWSMLRQSGQLSTHRELCLAVGFGMRIALEPCGRNETVRRSQRWVRLGTHLLHAESHLCLD 527
                    |.:.|.|  .||...|......|.::.|.:.  .:.::||......:.:.:|..|:.
 Worm   495 --------LSKEGNL--RRENTCASEENGNIRMKTCSKK--AQFNERWAYENKMIRNLKSGKCMS 547

  Fly   528 NP-LK--DRLEMSTCRSHAVSQSFQF 550
            .. ||  |...:..|......|.:.|
 Worm   548 TANLKPGDNAIVVECDEKDEHQKWNF 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	122/319 (38%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	27/140 (19%)
gly-9	NP_001022876.1	pp-GalNAc-T	137..438	CDD:133004	122/320 (38%)
		beta-trefoil_Ricin_Pgant1-like	445..575	CDD:467337	28/144 (19%)