Protein Alignment CG10000 and Galnt4

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_056552.1
• Gene: Galnt4 / 14426
• MGIID: 894692
• Length: 578
• Species: Mus musculus
• Alignment Length: 509
• Identity: 167/509 - (32%)
• Similarity: 257/509 - (50%)
• Gaps: 63/509 - (12%)

  Fly    73 YQYNIHLSNALGLIRKLPVTRHHSCTTRN---SILPAPLEANVSVVISFHNEARSMLLRTIVSLL 134
            |..||:||:.:.|.|.:...|.:.|..:.   ..||     ..||:|:|:|||.|.|||||.|:|
Mouse   100 YAINIYLSDRISLHRHIEDKRMYECKAKKFHYRSLP-----TTSVIIAFYNEAWSTLLRTIHSVL 159

  Fly   135 SRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASL 199
            ..||...|.|:|||||.|.| :.|...|:.::..:  .|.||    :|..:|.||:.:|..||:.
Mouse   160 ETSPAVLLKEIILVDDLSDR-IYLKAQLETYISNL--ERVRL----IRTNKREGLVRARLIGATF 217

  Fly   200 ASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLS-YRKGNELLKGGFDWSL 263
            |:|..:.|||.|||.|.|||||||||::.:....|.|::|.||..|.. |.:..|.:.|||||.|
Mouse   218 ATGDVLTFLDCHCECNTGWLEPLLERISRDETAIVCPVIDTIDWNTFEFYMQTGEPMIGGFDWRL 282

  Fly   264 HFHW---LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWL 325
            .|.|   .|.:...:.|...|.:||..|||:..:|:::|..||:::..:::||||::||:.::|.
Mouse   283 TFQWHSVPKHERDRRTSRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQ 347

  Fly   326 CGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPA 390
            |||::||.|||.:||:|.:|..:            |:..:|.|:...||.|:||||..||...|.
Mouse   348 CGGKLEIHPCSHVGHVFPKRAPY------------ARPNFLQNTARAAEVWMDEYKEHFYNRNPP 400

  Fly   391 ARRIPLDHTYDELQR---MRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN---EDRCVHAR 449
            ||:    ..|.:|..   :|:..:|..|:|||::|...|.:..|.....|.:|:   ...|:...
Mouse   401 ARK----EAYGDLSERKLLRERLKCKSFDWYLKNVFSNLHVPEDRPGWHGAIRSMGISSECLDYN 461

  Fly   450 QKDSQPI-----LASCYLSDITQWSMLRQSGQL--STHRELCLAVGFGM-RIALEPC---GRNET 503
            ..|:.|.     |..|:.....|:.....:.::  ::..|||..|.... .:.::.|   |....
Mouse   462 APDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPQQKDYVGMQNCPKDGLPVP 526

  Fly   504 VRRSQRWVRLGTHLLHAESHLCLD-------NPLKDRLEMSTCRSHAVSQSFQF 550
            |.....:...|| :.|..:.|||.       .|   .:.|.||.:...:|.::|
Mouse   527 VNIIWHFKEDGT-IFHPHTRLCLSAYRTAEGRP---SVHMKTCDALDKNQLWRF 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	126/315 (40%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	26/138 (19%)
Galnt4	NP_056552.1	Catalytic subdomain A	134..243		56/120 (47%)
		pp-GalNAc-T	138..432	CDD:133004	126/316 (40%)
		Catalytic subdomain B	303..365		27/61 (44%)
		beta-trefoil_Ricin-like	442..577	CDD:483949	27/139 (19%)