Protein Alignment CG10000 and Pgant35A

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_313714.6
• Gene: Pgant35A / 1274571
• VectorBaseID: AGAMI1_002567
• Length: 663
• Species: Anopheles gambiae
• Alignment Length: 553
• Identity: 174/553 - (31%)
• Similarity: 275/553 - (49%)
• Gaps: 96/553 - (17%)

  Fly    46 FMNESEESDHLDWRVFISH-----------TPETSEDF------------------YQYNIHLSN 81
            ||:|.|:..       |||           .|..:::|                  :.:|:.:||
Mosquito   111 FMHEKEKRR-------ISHRLIDELQPMLIQPNGTDEFGMVQNSEEQFIRDIGYRKHAFNVLVSN 168

  Fly    82 ALGLIRKLPVTRHHSCTTR--NSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHE 144
            .||..|.:|.|||..|..:  :.:||.     .|||:.|:||....|:|:|.::|.|:|...|.|
Mosquito   169 KLGPFRPIPDTRHKLCQAQVYDKVLPV-----ASVVMCFYNEHLETLVRSIHTVLKRTPAYLLKE 228

  Fly   145 LILVDDGSQ-RDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFL 208
            ||||||.|. .|:|:...|::.:..:..::.||    |||.:|.||:.||..||..|:|:.::||
Mosquito   229 LILVDDCSDFEDLTVGGQLEKELAQLGTNKVRL----LRNTDREGLMRSRVYGARNATGQVLIFL 289

  Fly   209 DSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHW---LKR 270
            |||.|||..|:||||.|:..:..:...|::|.|:..|..| ..:.|::|||:|.|||.|   .|.
Mosquito   290 DSHIEVNVDWIEPLLARIKHDRTILAMPVIDIINSDTFVY-TASPLVRGGFNWGLHFKWDNLPKG 353

  Fly   271 QLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPC 335
            .|........|:.||..|||:..:.|.:|.:||.::..:.:||||::|::.:.|.|||.||::||
Mosquito   354 SLERDTDFVGPFNSPTMAGGLFAIDRAYFKELGEYDMGMDVWGGENLEISFRAWQCGGSIELLPC 418

  Fly   336 SRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTY 400
            |||||:||:|..:..|        ..|:|.:.||..:|..|:|:|...||..:|.|..:|..:.
Mosquito   419 SRIGHVFRKRRPYGSP--------DGQDTMIRNSLRLAHVWMDDYIRYFYEQQPQAHHVPYGNV- 474

  Fly   401 DELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNEDRCV--HARQKDSQPILASCYLS 463
            .|.||:|:...|.||.|||.::.|:||:..::.|:......:.:..  |:|:::        |::
Mosquito   475 SERQRLRERLGCKPFRWYLDNIYPQLRVPGEKTSSDARDATQPKFEPWHSRKRN--------YVA 531

  Fly   464 DITQWSMLRQSGQLSTHRELCLAVGF---------GMRIALEPCGRNETVRRSQRWVRLGTHLLH 519
            ..    .:|.|     :..|||:...         |..:.|:||.|    .:.|.|.......|.
Mosquito   532 SF----QIRLS-----NSSLCLSTELDSEKSLWKKGSGLVLQPCLR----VKHQTWYETEKSELV 583

  Fly   520 AESHLCLDNP---LKDRLEMSTCRSHAVSQSFQ 549
            ....||||.|   .|.|.:::.|......|:::
Mosquito   584 LGQLLCLDAPSSATKGRPKLNKCHEMGGDQAWK 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	123/312 (39%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	26/132 (20%)
Pgant35A	XP_313714.6	None