Protein Alignment CG10000 and GALNT15

DIOPT Version :9

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_473451.3
• Gene: GALNT15 / 117248
• HGNCID: 21531
• Length: 639
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 172/531 - (32%)
• Similarity: 260/531 - (48%)
• Gaps: 62/531 - (11%)

  Fly    49 ESEESDHLDWRVFISHTPETSEDFYQYNIH-------LSNALGLIRKLPVTRHHSCTTRNSILPA 106
            :.:|:...||...........|:...:::.       ||..:.|.|.||..||..|..::   |.
Human   126 QDKEAPKRDWGADEDGEVSEEEELTPFSLDPRGLQEALSARIPLQRALPEVRHPLCLQQH---PQ 187

  Fly   107 PLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFG 171
            ......||::.||:||.|.||||:.|:|...|..:|.|:|||||.||:     ..||..:
Human   188 DSLPTASVILCFHDEAWSTLLRTVHSILDTVPRAFLKEIILVDDLSQQ-----GQLKSAL----- 242

  Fly   172 SRY--RL-GLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLA 233
            |.|  || |:..||:.:|:|.|.:|..||:.|:|..::|:|:|||.:.|||||||.|:|.:.:..
Human   243 SEYVARLEGVKLLRSNKRLGAIRARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRIAGDRSRV 307

  Fly   234 VSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFHW------LKRQLTNQESLEMPYQSPAFAGGVL 292
            |||::|.||..|..|....:|.:|..||.|.|||      :::.|.:..|   |.:||...|.|:
Human   308 VSPVIDVIDWKTFQYYPSKDLQRGVLDWKLDFHWEPLPEHVRKALQSPIS---PIRSPVVPGEVV 369

  Fly   293 MMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQ 357
            .|.|.:|...|:::..:.:.|||::||:.|.|||||.:||:||||:|||:          |:...
Human   370 AMDRHYFQNTGAYDSLMSLRGGENLELSFKAWLCGGSVEILPCSRVGHIY----------QNQDS 424

  Fly   358 LSPA-QETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERR--CHPFEWYL 419
            .||. ||..|.|...|||:||..:|..||...|.|..:......|.::|::.:||  |..|.|:|
Human   425 HSPLDQEATLRNRVRIAETWLGSFKETFYKHSPEAFSLSKAEKPDCMERLQLQRRLGCRTFHWFL 489

  Fly   420 RHVSPELRMHFDELSATGTLRNE--DRCVHARQKDS----QPILASCYLSDITQWSMLRQSGQLS 478
            .:|.|||.......|.:|.|.|.  ..|...:.:..    ..:||.|  ||..|...|:.:.:..
Human   490 ANVYPELYPSEPRPSFSGKLHNTGLGLCADCQAEGDILGCPMVLAPC--SDSRQQQYLQHTSRKE 552

  Fly   479 TH----RELCLAVGFGMRIALEPCGRNETVRRSQRW-VRLGTHLLHAESHLCLDNPLKDR---LE 535
            .|    :.||.||. ..::.|:.|.........|.| .:....::|..|..|::..:::.   |.
Human   553 IHFGSPQHLCFAVR-QEQVILQNCTEEGLAIHQQHWDFQENGMIVHILSGKCMEAVVQENNKDLY 616

  Fly   536 MSTCRSHAVSQ 546
            :..|...|..|
Human   617 LRPCDGKARQQ 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	126/320 (39%)
		Ricin_B_lectin	435..548	CDD:279046	27/126 (21%)
GALNT15	NP_473451.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..155		4/28 (14%)
		Catalytic subdomain A	190..299		52/118 (44%)
		Glyco_tranf_2_3	191..447	CDD:290369	113/278 (41%)
		pp-GalNAc-T	194..493	CDD:133004	126/321 (39%)
		Catalytic subdomain B	358..420		29/71 (41%)
		Ricin_B_lectin	505..628	CDD:279046	27/126 (21%)
		RICIN	507..630	CDD:238092	27/124 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820