DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10000 and Galnt16

DIOPT Version :9

Sequence 1:NP_651630.3 Gene:CG10000 / 43394 FlyBaseID:FBgn0039596 Length:558 Species:Drosophila melanogaster
Sequence 2:NP_001074890.1 Gene:Galnt16 / 108760 MGIID:1917754 Length:558 Species:Mus musculus


Alignment Length:532 Identity:185/532 - (34%)
Similarity:283/532 - (53%) Gaps:78/532 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 SDHLDWRVFISHTP-ETSEDFYQ---YNIHLSNALGLIRKLPVTRHHSC--TTRNSILPAPLEAN 111
            |...|.:.::|... :..||.|:   :|...|:.|...|.:..|||:||  .:.:|.|||     
Mouse    65 SKGFDEKAYLSAKQLKPGEDPYRQHAFNQLESDKLSSDRPIRDTRHYSCPSLSYSSDLPA----- 124

  Fly   112 VSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQ--RDVTLLDDLKRWMGGVFGSRY 174
            .||:|:|||||||.||||:.|:|:|:|...:.|:|||||.|.  .|..||..:.:          
Mouse   125 TSVIITFHNEARSTLLRTVKSVLNRTPASLIQEIILVDDFSSDPEDCLLLTRIPK---------- 179

  Fly   175 RLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLD 239
               :..|||.:|.|||.||.|||.:|....:.|||||||||..||:|:|:|:..:....|||::|
Mouse   180 ---VKCLRNDKREGLIRSRVRGADVAGATVLTFLDSHCEVNVEWLQPMLQRVMEDHTRVVSPIID 241

  Fly   240 PIDPTTLSYRKGNELLKGGFDWSLHFHW----LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFL 300
            .|.....:|...:..|:|||||||||.|    |::::|..:..: |.::|..|||:.::.:.||.
Mouse   242 VISLDNFAYLAASADLRGGFDWSLHFKWEQIPLEQKMTRTDPTK-PIRTPVIAGGIFVIDKSWFN 305

  Fly   301 KLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETY 365
            .||.::..:.|||||:.||:.::|:|||.:|||||||:||:||:||.::||..:       ..||
Mouse   306 HLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGN-------ALTY 363

  Fly   366 LHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHF 430
            :.|:|..||.|:||||..:|..||:|...........::: ||:..|..|.|||.:|.|||.:..
Mouse   364 IRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQ-RKKMDCKSFRWYLENVYPELTVPV 427

  Fly   431 DELSATGTLRNEDRCVHARQKD-----------------SQPILASCYLSDITQWSMLRQSGQLS 478
            .|: ..|.::....|:.::.::                 |.|...:...||    .:::|.|:  
Mouse   428 KEV-LPGVIKQGVNCLESQGQNTAGDLLLGMGICRGSAKSPPPAQAWLFSD----HLIQQQGK-- 485

  Fly   479 THRELCLAV------GFGMRIALEPCGRNETVRRSQRWVRLGTHLLHAESHLCLDNPLKDRLEMS 537
                 |||.      ..|..:.|:.|...|   ..|:|.|.|:.:.|:.|.|||:.. ..:|..|
Mouse   486 -----CLAATSTLMSSPGSPVILQTCNPKE---GKQKWRRKGSFIQHSVSGLCLETK-PAQLVTS 541

  Fly   538 TCRSHAVSQSFQ 549
            .|::.|.:|.:|
Mouse   542 KCQTDAQAQQWQ 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10000NP_651630.3 pp-GalNAc-T 113..422 CDD:133004 131/314 (42%)
Ricin_B_lectin 435..548 CDD:279046 29/135 (21%)
Galnt16NP_001074890.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..53
Catalytic subdomain A 122..227 57/122 (47%)
pp-GalNAc-T 126..420 CDD:133004 131/315 (42%)
Catalytic subdomain B 286..348 29/61 (48%)
Ricin_B_lectin 441..552 CDD:306998 28/125 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3736
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D606683at2759
OrthoFinder 1 1.000 - - FOG0001204
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR11675
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
76.880

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