Protein Alignment CG10000 and Galnt2

DIOPT Version :10

• Sequence 1: NP_651630.3
• Gene: CG10000 / 43394
• FlyBaseID: FBgn0039596
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_644678.2
• Gene: Galnt2 / 108148
• MGIID: 894694
• Length: 570
• Species: Mus musculus
• Alignment Length: 507
• Identity: 183/507 - (36%)
• Similarity: 284/507 - (56%)
• Gaps: 49/507 - (9%)

  Fly    68 TSEDFY---QYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRT 129
            :.:|.|   ::|...|:.|.:.|.:|.|||..|..:...:..|.   .||||:|||||||.||||
Mouse    93 SGQDPYARNKFNQVESDKLHMDRGIPDTRHDQCQRKQWRVDLPA---TSVVITFHNEARSALLRT 154

  Fly   130 IVSLLSRSPEDYLHELILVDDGSQ--RDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWS 192
            :||:|.|||...:.|:|||||.|.  .|..||..:::             :..|||..|.||:.|
Mouse   155 VVSVLKRSPPHLIKEIILVDDYSNDPEDGALLGKIEK-------------VRVLRNDRREGLMRS 206

  Fly   193 RNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKG 257
            |.|||..|..:.:.|||||||.||.||||||||:|.:....|||::|.|:.....|...:..|||
Mouse   207 RVRGADAAQAKVLTFLDSHCECNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKG 271

  Fly   258 GFDWSLHFHW----LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIE 318
            ||||:|.|.|    .:::.:.|.:...|.::|..|||:.:|.:.:|.:||.::..:.:||||::|
Mouse   272 GFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLE 336

  Fly   319 LAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNM 383
            ::.::|.|||.:||:||||:||:||::|.:.||..|.       ..:..|::..||.|:||||:.
Mouse   337 ISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSG-------TVFARNTRRAAEVWMDEYKHF 394

  Fly   384 FYALRPAARRIPLDHTYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNEDRCVHA 448
            :||..|:||.:|..:....|: :||:..|.||:|||.:|.||||:...:..|.|.|:....|:..
Mouse   395 YYAAVPSARNVPYGNIQSRLE-LRKKLGCKPFKWYLDNVYPELRVPDHQDIAFGALQQGTNCLDT 458

  Fly   449 RQKDSQPILA--SCYLSDITQ-WSMLRQSGQLSTHRELCLAV---GFGMRIALEPCGRNETVRRS 507
            ....:..::.  .|:.:...| |::.::..  ..|.:|||.|   ..|..|.|:.|..|::   .
Mouse   459 LGHFADGVVGIYECHNAGGNQEWALTKEKS--VKHMDLCLTVVDRSPGSLIRLQGCRENDS---R 518

  Fly   508 QRWVRL--GTHLLHAESHLCLDN--PLKDRLEMSTCRSHAVSQSFQFALEME 555
            |:|.::  .:.|.|..|:||||:  .....|.:..| ..|:||.::|:|.::
Mouse   519 QKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVC-GPALSQQWKFSLNLQ 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	133/314 (42%)
		beta-trefoil_Ricin-like	432..550	CDD:483949	31/127 (24%)
Galnt2	NP_644678.2	Catalytic subdomain A	134..239		59/120 (49%)
		pp-GalNAc-T	138..433	CDD:133004	133/315 (42%)
		Catalytic subdomain B	299..361		26/61 (43%)
		beta-trefoil_Ricin_GALNT2	445..564	CDD:467312	31/124 (25%)