DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt9

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_002931923.1	Gene:	galnt9 / 100490061	XenbaseID:	XB-GENE-948907	Length:	604	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	149/532 - (28%)
Similarity:	241/532 - (45%)	Gaps:	117/532 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 SHTPETSEDFYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLL 127
            ||..||..:.|.||..||:.:.|.|.:|..|...|  :....|..| ..::||..|.|||.|::|
Frog   108 SHESETKYEEYGYNAQLSDRISLDRSIPDYRPKKC--KQMTYPDDL-PQIAVVFIFVNEALSVIL 169

  Fly   128 RTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWS 192
            |::.|:::.:|...|.|:|||||.|. :|.|..:|.:::    ..||...:..:||..|.|||.:
Frog   170 RSVHSVVNHTPSYLLKEIILVDDNSD-NVELKFNLDQYV----NKRYPGLVKIVRNTRREGLIRA 229

  Fly   193 RNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKG 257
            |.:|...||...|.|.|:|.|.|.||.||::.|:..:....:.|.:|.|...:...::......
Frog   230 RIQGWKAASAPIVGFFDAHVEFNTGWAEPVITRIKEDRRRIILPAIDNIKYNSFEVQQYANAAH- 293

  Fly   258 GFDWSLHFHWLKRQLTNQESLE-----MPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESI 317
            |::|.|   |.......|:.||     .|.::||..|...::.|.:|..:|..:|.::::|||:|
Frog   294 GYNWGL---WCMYITPPQDWLEKGDESAPIRTPAMIGCSFVVDRAYFGDIGLLDPGMEVYGGENI 355

  Fly   318 ELAIKLWLCGGQIEIVPCSRIGHIFRRRHAF--DFPPQSDRQLSPAQETYLHNSKIIAESWLDEY 380
            ||.:::|.|||.:|::||||:.||.|.:..:  |....:.|           |:...||.|:||:
Frog   356 ELGMRVWQCGGSMEVLPCSRVAHIERTKKPYNNDIDYYAKR-----------NALRAAEVWMDEF 409

  Fly   381 KNMFYALRPAARRIPLDH------TYDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTL 439
            |:..|    .|..||:.:      ...|...:|::.:|..|:|||.:|.||:|::.:.:: .|.|
Frog   410 KSHVY----MAWNIPMTNPGVDFGDVSERVALRQKLQCRSFKWYLENVYPEMRVYNNTIT-YGEL 469

  Fly   440 RN------------ED---------------------------------------RCVHARQKDS 453
            ||            ||                                       :|:....|..
Frog   470 RNSKATGYCLDQGSEDDNKAILYPCHGMSSQLVRYSSEGLLQLGPLGSTSFLPDTKCLIDDGKGR 534

  Fly   454 QPILASC--------YLSDITQWSML--RQSGQLSTHRELCLAV------GFGMRIALEPCGRNE 502
            .|.|..|        .|.|.||.|.:  |.:|:       ||.|      .||:|:.::.|...:
Frog   535 TPTLKKCDDVPRSPQKLWDFTQSSPIVNRDTGR-------CLEVEMSKDANFGLRLVVQRCSGQK 592

  Fly   503 TVRRSQRWVRLG 514
            .:.|:  |::.|
Frog   593 WIIRN--WIKHG 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	101/321 (31%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	28/147 (19%)
galnt9	XP_002931923.1	pp-GalNAc-T	156..454	CDD:133004	101/321 (31%)
galnt9	XP_002931923.1	Ricin_B_lectin	465..593	CDD:366226	25/135 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910