DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10000 and galnt18

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_031756257.1	Gene:	galnt18 / 100488804	XenbaseID:	XB-GENE-959491	Length:	608	Species:	Xenopus tropicalis

Alignment Length:	477	Identity:	152/477 - (31%)
Similarity:	234/477 - (49%)	Gaps:	43/477 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 FYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSR 136
            :|.||.:||:.|.|.|.||..|...|  :|...|..| ..:|||..|.|||.|::||:|.|.::|
Frog   118 YYGYNAYLSDRLPLDRPLPDFRPAGC--KNLTFPEDL-PQISVVFIFVNEAFSVILRSINSAINR 179

  Fly   137 SPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLAS 201
            :|...|.|:|||||.|..: .|...|.:::.. |..|....:..:|:.::.|||.||..|...|:
Frog   180 TPAKLLKEIILVDDNSSNE-ELRTKLAQYVED-FNKRKPGFIKVVRHSKQEGLIRSRVSGWRAAT 242

  Fly   202 GRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSLHFH 266
            ...|...|||.|.|.||.||:|.|:..:....:||..|.|:.......: ..|...||||.|...
Frog   243 APVVALFDSHIEFNVGWAEPVLLRIKEDRTRVISPSFDNINYDDFELEQ-YPLNAQGFDWQLWCR 306

  Fly   267 WLK--RQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQ 329
            :|.  :....||:...|.::|:.. |..::.|.:|.::|..:..:.|:|||::|||:::|.|||.
Frog   307 YLNPPKSWFKQENKTAPIRTPSLI-GCFIVDRLYFEEIGLLDEGMDIYGGENVELAVRVWQCGGS 370

  Fly   330 IEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRI 394
            :|::|||||.||.|....:      ..||:   |....|:..:||.|:||:|:..|    .|..|
Frog   371 VEVIPCSRIAHIERAHKPY------TGQLA---EHVRRNALRVAEVWMDEFKSHVY----MAWNI 422

  Fly   395 PLDHT------YDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNEDR---CV-HAR 449
            |.:.:      ....:.:||:.:|..|.|||..|.||:|.:.| :.|.|:|:|..:   |: ...
Frog   423 PQEDSGIDFGDISSRKALRKKLQCKTFRWYLVSVYPEMRTYSD-IIAYGSLKNSVKAGLCLDQGP 486

  Fly   450 QKDSQPILASC--YLSDITQWSMLRQ--SGQLSTHRE----LCLAVGFGMRIALEPCGRNETVRR 506
            ..|:.||:..|  |:.....::..:|  .|.||...:    .|| |....|..|..|...:..|.
Frog   487 DTDNTPIVYLCHGYVPQSIYYTSTQQLHIGALSPTIDDVDIKCL-VDVNSRPRLIECNYAKAKRM 550

  Fly   507 SQRW-VRLGTHLLHAESHLCLD 527
            ...| ...|..:.:.:|..||:
Frog   551 KLYWDFNQGGPIQNKKSKRCLE 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	106/316 (34%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	26/106 (25%)
galnt18	XP_031756257.1	pp-GalNAc-T	156..457	CDD:133004	106/317 (33%)
galnt18	XP_031756257.1	RICIN	470..597	CDD:238092	25/104 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010