DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt3

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_002936794.2	Gene:	galnt3 / 100488466	XenbaseID:	XB-GENE-954414	Length:	625	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	173/532 - (32%)
Similarity:	262/532 - (49%)	Gaps:	62/532 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SANELLSFMNESEESDHLD---WRVFISH--TPETSED------FYQYNIHLSNALGLIRKL-PV 91
            :|.||..|:....:..|..   .:.|...  |||..|:      .:.:|...::.:.|.|.| |.
Frog    95 TAAELKPFLERPPQDPHAPGAAGKPFKEEKLTPEEQEEKERGEKKHCFNAFATDRISLHRDLGPD 159

  Fly    92 TRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDV 156
            ||...|..:......|| ...|::|.|||||.|.||||:.|::..||...|.|:|||||.|. |.
Frog   160 TRPPECIEQKFKRCPPL-PTTSIIIVFHNEAWSTLLRTVYSVMHTSPAILLKEIILVDDASV-DE 222

  Fly   157 TLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEP 221
            .|.|:|..::     .:.:: :..:|.:||.|||.:|..|||:|:|..:.|||:|||...|||||
Frog   223 YLKDELDEYV-----KQLQI-VKVVRQKERKGLITARLLGASVATGDTLTFLDAHCECYYGWLEP 281

  Fly   222 LLERLALNTNLAVSPLLDPIDPTTLSYRK----GNELLKGGFDWSLHFHW---LKRQLTNQESLE 279
            ||.|:|.|....|||.:..||..|..:..    ||...:|.|||:|.|.|   ...:.|.::...
Frog   282 LLARIAENYTSVVSPDITGIDLNTFQFSNPSPYGNNHNRGNFDWTLSFGWESLPSSEKTRRKDET 346

  Fly   280 MPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRR 344
            .|.::|.||||:..:|:.:|..:||::..::|||||:||::.::|.||||:||:|||.:||:||.
Frog   347 YPIKTPTFAGGLFSISKAYFEHIGSYDEQMEIWGGENIEMSFRVWQCGGQLEILPCSVVGHVFRS 411

  Fly   345 RHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQR---M 406
            :....||        ...:..:.|...:||.|:|:.|.:||.....|..|.....|.:|.:   :
Frog   412 KSPHTFP--------KGTQVIVRNQVRLAEVWMDDLKEIFYRRNREAANIVKSKEYGDLSKRLDL 468

  Fly   407 RKERRCHPFEWYLRHVSPELRMHFDELSATGTLRN--EDRCVHA---RQKDSQPILASCY----- 461
            |...:|..|.|||.::.||:.:........|.|:|  .|.|:..   ...|...|:.||:
Frog   469 RHRLQCKNFTWYLNNIYPEMYVPERHPLIHGDLKNVGRDLCLDVGGENHGDKPLIMYSCHGLGGN 533

  Fly   462 -LSDITQWSMLRQSGQLSTHRELCLAVGFGMRIALEPC---GRNETVRRSQRWVRLGTHLLHAES 522
             ..:.|....:|.:.|    :||||..... .:.::||   ||:......:||......||...|
Frog   534 QYFEYTSKHEIRHNIQ----KELCLRPSHS-SLVIKPCNYRGRDTAPLPEERWELQREQLLFNPS 593

  Fly   523 H-LCLD----NP 529
            : ||:.    ||
Frog   594 YNLCVSSEGANP 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	122/318 (38%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	29/114 (25%)
galnt3	XP_002936794.2	pp-GalNAc-T	180..485	CDD:133004	122/319 (38%)
galnt3	XP_002936794.2	Ricin_B_lectin	498..619	CDD:366226	29/113 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010