DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and Galnt6

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	517	Identity:	172/517 - (33%)
Similarity:	265/517 - (51%)	Gaps:	64/517 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DWRVFISHTPETSEDF--YQYNIHLSNALGLIRKL-PVTRHHSCTTRNSILPAPLEANVSVVISF 118
            :|.:.  .|.|..|.:  :.:|...|:.:.|.|.| |.||...|..:......|| ...||||.|
  Rat   124 EWTLL--ETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPL-PTTSVVIVF 185

  Fly   119 HNEARSMLLRTIVSLLSRSPEDYLHELILVDDGSQRDVTLLDDLKRWMGGVFGSRYRLGLTFLRN 183
            ||||.|.||||:.|:|..||...|.|:|||||.| .|..|.:.|:|::     .:.:: :..:|.
  Rat   186 HNEAWSTLLRTVYSVLHTSPAILLKEIILVDDAS-TDEHLKEKLERYV-----QQLQI-VRVVRQ 243

  Fly   184 QERMGLIWSRNRGASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSY 248
            |||.|||.:|..|||:|....:.|||:|||...|||||||.|:|.:....|||.:..||..|..:
  Rat   244 QERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQF 308

  Fly   249 ----RKGNELLKGGFDWSLHFHW-----LKRQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGS 304
                |:|....:|.|||||.|.|     .::|....|:  .|.:||.||||:..:|:.:|..:|:
  Rat   309 SKPMRRGKAHSRGNFDWSLTFGWEMLPEHEKQRRKDET--YPIKSPTFAGGLFSISKAYFEHIGT 371

  Fly   305 FNPYLKIWGGESIELAIKLWLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNS 369
            ::..::|||||::|::.::|.||||:||:|||.:||:||.:....||        ........|.
  Rat   372 YDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFP--------KGTSVIARNQ 428

  Fly   370 KIIAESWLDEYKNMFYALRPAARRIPLDHTYDELQ---RMRKERRCHPFEWYLRHVSPELRMHFD 431
            ..:||.|:|:||.:||.....|.::..::.:.::.   |:|::..||.|.|||.:|.||  |...
  Rat   429 VRLAEVWMDDYKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPE--MFVP 491

  Fly   432 ELSAT--GTLRN--EDRC--VHARQKDSQPIL--------ASCYLSDITQWSMLRQSGQLSTHRE 482
            :|:.|  |.::|  ..:|  |....:..:|::        .:.|....:|..:....|     ::
  Rat   492 DLNPTFSGAIKNLGTSQCLDVGENNRGGKPLIMYVCHNLGGNQYFEYTSQRDLRHNIG-----KQ 551

  Fly   483 LCLAVGFGMRIALEPC---GRNETVRRSQRWVRLGTHLL-HAESHLCLDNPLKDRL-EMSTC 539
            |||... |..:.|..|   |:|..|.:.:.|......|: :..|..||.:  ||:. .|:.|
  Rat   552 LCLHAS-GSTLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGTCLTS--KDKKPAMAPC 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	125/320 (39%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	27/124 (22%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	125/321 (39%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	26/122 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920