DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10000 and galnt18b

DIOPT Version :9

Sequence 1:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	XP_003199061.1	Gene:	galnt18b / 100310831	ZFINID:	ZDB-GENE-091014-1	Length:	609	Species:	Danio rerio

Alignment Length:	527	Identity:	158/527 - (29%)
Similarity:	243/527 - (46%)	Gaps:	79/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 FYQYNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLEANVSVVISFHNEARSMLLRTIVSLLSR 136
            :|.||.:||:.|.:.|.:|..|...|  :|...|:.| ..||:|..|.|||.|::||:|.|:::|
Zfish   121 YYGYNGYLSDRLSMDRAIPDYRPDGC--KNMSYPSNL-PQVSIVFIFVNEALSVILRSIHSVMNR 182

  Fly   137 SPEDYLHELILVDDGSQRD---VTLLDDLKRWMGGVFGSRYRLGLTFLRNQERMGLIWSRNRGAS 198
            :|...|.|:|||||.|..|   ..|.|.:|.......|.     :..:|:..:.|||.||..|..
Zfish   183 TPSHLLKEIILVDDNSNNDELKEKLQDFVKETNAKQPGF-----IKVVRHSRQEGLIRSRVSGWR 242

  Fly   199 LASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFDWSL 263
            .||...|...|:|.|.|.||.||:|:|:..:....:||..|.|...|....: ..|...||||.|
Zfish   243 AASAPVVALFDAHVEFNIGWAEPILQRIKEDRTRIISPSFDNIKYDTFEIEE-YPLSAQGFDWEL 306

  Fly   264 HFHWLK--RQLTNQESLEMPYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKLWLC 326
            ...:|.  :...|..:...|.:|||.. |..::.|.:|.::|..:..::|:|||::||.:::|.|
Zfish   307 WCRYLNPPKSWWNLNNSTAPIRSPALI-GCFVVDRLYFAEIGLLDEGMEIYGGENVELGVRVWQC 370

  Fly   327 GGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLH---NSKIIAESWLDEYKNMFYALR 388
            ||.:|::||:||.||.|....:            .::...|   |:..:||.|:||:|:..|
Zfish   371 GGSVEVLPCARIAHIERAHKPY------------TEDLTAHVRRNALRVAEVWMDEFKSHVY--- 420

  Fly   389 PAARRIPLDHT------YDELQRMRKERRCHPFEWYLRHVSPELRMHFDELSATGTLRNE---DR 444
             .|..||.:.:      ..|.:.:||:.:|..|.|||.::.||:||:.|.: |.|.|||.   |.
Zfish   421 -MAWNIPQEDSGIDIGDIAERKALRKKLQCKTFRWYLVNIYPEMRMYTDTV-AYGVLRNSLKTDL 483

  Fly   445 CV-HARQKDSQPILASCYLSDITQWSMLRQSGQLSTHREL---------------CLAVGFGMRI 493
            |: .....|:.|||..|:       .|..|:...::.::|               || |....|.
Zfish   484 CLDQGPDTDNIPILYLCH-------GMTPQNVYYTSTQQLFVGILSPTVDDDDNKCL-VDVNGRP 540

  Fly   494 ALEPCGRNETVRRSQRW-VRLGTHLLHAESHLCL------DNPLKDRLEMSTCRSHAVSQSFQFA 551
            .|..|......|....| ...|..:.:.:|..||      ||....:|.:..|    ..|::...
Zfish   541 RLIECSYAVAKRMKLHWRFTQGGSIQNTKSKRCLELVENNDNEFGFQLTLQKC----TGQNWTIT 601

  Fly   552 LEMEGQT 558
            ..:.|.|
Zfish   602 NMLPGST 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	105/322 (33%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	32/138 (23%)
galnt18b	XP_003199061.1	pp-GalNAc-T	159..460	CDD:133004	105/323 (33%)
		Glyco_tranf_2_2	160..421	CDD:287123	93/283 (33%)
		Ricin_B_lectin	471..598	CDD:279046	32/138 (23%)
		RICIN	473..600	CDD:238092	31/138 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900