DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R2 and MCHR2

DIOPT Version :9

Sequence 1:NP_001263042.1 Gene:AstA-R2 / 43393 FlyBaseID:FBgn0039595 Length:357 Species:Drosophila melanogaster
Sequence 2:NP_001035269.1 Gene:MCHR2 / 84539 HGNCID:20867 Length:340 Species:Homo sapiens


Alignment Length:313 Identity:87/313 - (27%)
Similarity:144/313 - (46%) Gaps:41/313 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYW 104
            |:....|:|..||..||:|::..:: .:..::..::.|.|||.|||:.:: .:||     :::.|
Human    36 ILPSMIGIICSTGLVGNILIVFTII-RSRKKTVPDIYICNLAVADLVHIV-GMPF-----LIHQW 93

  Fly   105 PYGRFW------CRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLW 163
            ..|..|      |..:..|.....||....:.:||:||:.|:|.|.|....||...|:...:.||
Human    94 ARGGEWVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLW 158

  Fly   164 IVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRT---YQVTFFISSYLLPLMIISG 225
            ....::::||.....|:...|..::     |.|   |...|..   |.:...|:::..||.:|..
Human   159 AASFILALPVWVYSKVIKFKDGVES-----CAF---DLTSPDDVLWYTLYLTITTFFFPLPLILV 215

  Fly   226 LYMRMIMRLW---RQGTGVRMSKES---QRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVI 284
            .|:.::...|   :|....|....|   ||..| :|::|:|:|:.|.....|..:|.|:..  .:
Human   216 CYILILCYTWEMYQQNKDARCCNPSVPKQRVMK-LTKMVLVLVVVFILSAAPYHVIQLVNL--QM 277

  Fly   285 ETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENF--------RKAFYKAVN 329
            |..||...|....:..|:|:||.|||.||..||.||        |:|..|.:|
Human   278 EQPTLAFYVGYYLSICLSYASSSINPFLYILLSGNFQKRLPQIQRRATEKEIN 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R2NP_001263042.1 7tm_4 47..>164 CDD:304433 34/122 (28%)
7tm_1 55..313 CDD:278431 72/272 (26%)
MCHR2NP_001035269.1 7tmA_MCHR2 35..317 CDD:320461 83/298 (28%)
TM helix 1 36..62 CDD:320461 8/26 (31%)
TM helix 2 68..94 CDD:320461 9/31 (29%)
TM helix 3 106..136 CDD:320461 9/29 (31%)
TM helix 4 148..168 CDD:320461 3/19 (16%)
TM helix 5 194..223 CDD:320461 6/28 (21%)
TM helix 6 244..274 CDD:320461 11/30 (37%)
TM helix 7 285..310 CDD:320461 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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