Protein Alignment AstA-R2 and Ackr3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_445804.1
• Gene: Ackr3 / 84348
• RGDID: 620601
• Length: 362
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 74/303 - (24%)
• Similarity: 133/303 - (43%)
• Gaps: 28/303 - (9%)

  Fly    37 LPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMV 101
            |.:.:.|.:..|.:.|...|.:|:.|.:........|:..|:|||.||| :|::.||......:.
  Rat    43 LLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADL-WVVITIPVWVVSLVQ 106

  Fly   102 Y-YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIV 165
            : .||.|...|:....:..:..|.||:.|..||:||:|::.:...:...:.:.:..:..|.:|::
  Rat   107 HNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTSTSSYKKKMVRRVVCVLVWLL 171

  Fly   166 VLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND----FLGPRTYQVTFFISSYLLPLMIISGL 226
            ...||:|..:....|.  .|..|.||....:..:.    .:|.....|   |..:.:|..||:..
  Rat   172 AFFVSLPDTYYLKTVT--SASNNETYCRSFYPEHSIKEWLIGMELVSV---ILGFAVPFTIIAIF 231

  Fly   227 YMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVI------- 284
            |..:...:...|     .:|....||.:...|||.::.    |||...::||....::
  Rat   232 YFLLARAMSASG-----DQEKHSSRKIIFSYVVVFLVC----WLPYHFVVLLDIFSILHYIPFTC 287

  Fly   285 ETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKA 327
            :...:....:.|| |.|:....|:||:||:|::.|:|....||
  Rat   288 QLENVLFTALHVT-QCLSLVHCCVNPVLYSFINRNYRYELMKA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	71/296 (24%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
Ackr3	NP_445804.1	7tmA_ACKR3_CXCR7	45..326	CDD:320118	71/296 (24%)
		TM helix 1	46..72	CDD:320118	6/25 (24%)
		TM helix 2	79..103	CDD:320118	11/24 (46%)
		TM helix 3	117..147	CDD:320118	10/29 (34%)
		TM helix 4	160..181	CDD:320118	5/20 (25%)
		TM helix 5	209..236	CDD:320118	7/29 (24%)
		TM helix 6	245..275	CDD:320118	10/33 (30%)
		TM helix 7	294..319	CDD:320118	10/25 (40%)
		C-terminal cytoplasmic tail. /evidence=ECO:0000250	324..362		2/6 (33%)