Protein Alignment AstA-R2 and QRFPR

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_937822.2
• Gene: QRFPR / 84109
• HGNCID: 15565
• Length: 431
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 91/333 - (27%)
• Similarity: 150/333 - (45%)
• Gaps: 36/333 - (10%)

  Fly    26 TDEEWLAINGTLPWIV-----GFFFGVIAITG-------FFGNLLVILVVVFNNNMRSTTNLMIV 78
            |.|:::|:....|.:.     |.....:.:||       .|||.||..||..:..||:.||:.|.
Human    21 TREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFIC 85

  Fly    79 NLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHP 143
            :||.:||:....|||.|....:...|..|.|.|:.|.::........|.|:..::::|...:|||
Human    86 SLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHP 150

  Fly   144 IRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQ 208
            .:.:...|.......:..:|:|.::|..|:.....:.:.||......:..|.......:..:.|.
Human   151 FKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYT 215

  Fly   209 VTFFISSYLLPLMIISGLYMRMIMRLW---RQGT--------GVRMSKESQRGRKRVTRLVVVVV 262
            ....:..:|||||::..||.::...||   |.|.        |..|||.: |.:||...::|.||
Human   216 TFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIA-RKKKRAVIMMVTVV 279

  Fly   263 IAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVT-------AQTLAYSSSCINPLLYAFLSENF 320
            ..||..|.|..::.::     ||.:...|....||       .|.:.:|:|..||::|||::|||
Human   280 ALFAVCWAPFHVVHMM-----IEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENF 339

  Fly   321 RKAFYKAV 328
            :|....||
Human   340 KKNVLSAV 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	85/314 (27%)
		TM helix 1	40..66	CDD:320224	10/37 (27%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	5/29 (17%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	10/31 (32%)
QRFPR	NP_937822.2	7tmA_QRFPR	46..343	CDD:320333	84/302 (28%)
		TM helix 1	47..73	CDD:320333	9/25 (36%)
		TM helix 2	80..106	CDD:320333	11/25 (44%)
		TM helix 3	118..148	CDD:320333	5/29 (17%)
		TM helix 4	161..182	CDD:320333	4/20 (20%)
		TM helix 5	211..236	CDD:320333	8/24 (33%)
		TM helix 6	266..296	CDD:320333	10/34 (29%)
		TM helix 7	311..336	CDD:320333	8/24 (33%)