Protein Alignment AstA-R2 and Gpr84

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_109645.1
• Gene: Gpr84 / 80910
• MGIID: 1934129
• Length: 396
• Species: Mus musculus
• Alignment Length: 393
• Identity: 87/393 - (22%)
• Similarity: 147/393 - (37%)
• Gaps: 135/393 - (34%)

  Fly    40 IVGF-FFGVI-----AITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATD 98
            ::|: :|.:|     |:||..||:|.:|.:.....:|:..||:|.||..|||::..|..||:...
Mouse    16 VLGYRYFAIIWGVAVAVTGTVGNVLTLLALAIRPKLRTRFNLLIANLTLADLLYCTLLQPFSVDT 80

  Fly    99 YMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHP-IRSRMMRTENITLIAIVTL 162
            |:..:|..|..:||....|:..:...||.||.|:::.|:|.:.|| :..::...:.|.| |:|..
Mouse    81 YLHLHWRTGAVFCRIFGLLLFTSNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVL-ALVGS 144

  Fly   163 WIVVLV---------VSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLL 218
            |:|.:.         |.|||..|                 |:|   |.:..|.|........::|
Mouse   145 WVVGVTSFAPLWNVFVLVPVVCT-----------------CSF---DRMRGRPYTTILMGIYFVL 189

  Fly   219 PLMIISGLYM---RMIMRLWRQ------------------------------------------- 237
            .|..:...|.   |.:.|..|.
Mouse   190 GLSSVGVFYCLIHRQVKRAARALDQYGLHQASIRSHQVAGTQEAMPGHFQELDSGVASRGPSEGI 254

  Fly   238 ---------------------GTGVRMS----------------KESQRGRK---------RVTR 256
                                 |.|:|.:                :|:...|:         :|||
Mouse   255 SSEPVSAATTQTLEGDSSEAGGQGIRKAAQQIAERSLPEVHRKPRETAGARRATDAPSEFGKVTR 319

  Fly   257 LVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFR 321
            :...|.:.||..::|..|      |::::.......|:.:.|..|.:.:|||||:|||.::..||
Mouse   320 MCFAVFLCFALSYIPFLL------LNILDARGRAPRVVHMVAANLTWLNSCINPVLYAAMNRQFR 378

  Fly   322 KAF 324
            .|:
Mouse   379 HAY 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	86/391 (22%)
		TM helix 1	40..66	CDD:320224	10/31 (32%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	8/28 (29%)
		TM helix 5	204..233	CDD:320224	6/31 (19%)
		TM helix 6	249..279	CDD:320224	9/38 (24%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
Gpr84	NP_109645.1	7tmA_GPR84-like	21..381	CDD:320338	85/386 (22%)
		TM helix 1	22..48	CDD:320338	9/25 (36%)
		TM helix 2	55..78	CDD:320338	11/22 (50%)
		TM helix 3	93..123	CDD:320338	10/29 (34%)
		TM helix 4	137..155	CDD:320338	6/18 (33%)
		TM helix 5	175..200	CDD:320338	5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..310		5/68 (7%)
		TM helix 6	312..342	CDD:320338	9/35 (26%)
		TM helix 7	349..374	CDD:320338	11/24 (46%)