Protein Alignment AstA-R2 and prlh2r

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001108619.1
• Gene: prlh2r / 797157
• ZFINID: ZDB-GENE-120411-41
• Length: 371
• Species: Danio rerio
• Alignment Length: 364
• Identity: 111/364 - (30%)
• Similarity: 179/364 - (49%)
• Gaps: 50/364 - (13%)

  Fly     9 NISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTT 73
            ||||:.:      :|.||..:.|.  ...|..:. .:.::.:....||||:::::..|..:.|||
Zfish    14 NISLDLS------SSSFTGLQLLM--DLKPLFIP-LYTMLVLIACSGNLLLLILIGLNKKLHSTT 69

  Fly    74 NLMIVNLAAADLMFVILCIPFTATDYMVYY------WPYGRFWCRSVQYLIVVTAFASIYTLVLM 132
            |.:|.|||..||:..:.|:|.||     :|      |.:|:|.|..|..:...|.||::.:|..:
Zfish    70 NFLIGNLALVDLVMCLFCVPLTA-----FYAFDERGWVFGQFMCHFVTLMQTATVFAAVLSLTAI 129

  Fly   133 SIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMC-TF 196
            ::||::.|.:|||.|..|.....|  :|::|:..|.:|.|.|. |.|.:|. ::......:| .|
Zfish   130 AVDRYVVVAYPIRRRGGRWFCGWL--VVSIWLCALAMSTPTAL-HTVYLDL-SETGHEMAVCEEF 190

  Fly   197 TTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRM----SKESQRGRKR--VT 255
            .....|....|...|.:.||.:||..:|..|..:...|..:.|...|    |.:.:.||||  ..
Zfish   191 WHGQELSRLIYSCFFLLLSYFVPLAAVSISYCAISCHLQHRATPRLMAATPSNQEKWGRKRRKTF 255

  Fly   256 RLVVVVVIAFASLWLPVQLILLLKSLD----VIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFL 316
            ||::|.|::||..|||:|::.|::.||    ::..|.:.  ||||:...||.||:|.||.:||.|
Zfish   256 RLLLVSVLSFAFSWLPLQIVNLIRDLDTDFAILSKNHVN--VIQVSCHLLAMSSACYNPFIYASL 318

  Fly   317 SENFRKAFYKAVNCSSRYQNYTSDLPPPRKTSCARTSTT 355
            .:.|....     |.:.:|.        ||..|.::|.|
Zfish   319 HKKFLSYL-----CHNMFQK--------RKAHCTQSSIT 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	95/301 (32%)
		TM helix 1	40..66	CDD:320224	4/25 (16%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	15/31 (48%)
		TM helix 7	292..317	CDD:320224	13/24 (54%)
prlh2r	NP_001108619.1	7tmA_PrRP_R	35..326	CDD:320516	96/302 (32%)
		TM helix 1	36..62	CDD:320516	4/26 (15%)
		TM helix 2	69..94	CDD:320516	12/29 (41%)
		TM helix 3	108..138	CDD:320516	8/29 (28%)
		TM helix 4	149..170	CDD:320516	6/22 (27%)
		TM helix 5	198..227	CDD:320516	8/28 (29%)
		TM helix 6	249..279	CDD:320516	14/29 (48%)
		TM helix 7	294..319	CDD:320516	13/26 (50%)