Protein Alignment AstA-R2 and SSTR2

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001041.1
• Gene: SSTR2 / 6752
• HGNCID: 11331
• Length: 369
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 107/325 - (32%)
• Similarity: 173/325 - (53%)
• Gaps: 45/325 - (13%)

  Fly    30 WLAI--------------NGTLPW-------IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTT 73
            ||:|              |.|.|:       ::.|.:.|:.|.|..||.|||.|::....|::.|
Human    14 WLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTIT 78

  Fly    74 NLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFL 138
            |:.|:|||.||.:| :|.:||.|....:.:||:|:..||.|..:..:..|.||:.|.:|||||:|
Human    79 NIYILNLAIADELF-MLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYL 142

  Fly   139 AVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTN---- 199
            ||||||:|...|......:..:.:|.|.|:|.:|:..       |...::..:|..:.|.|
Human   143 AVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMI-------YAGLRSNQWGRSSCTINWPGE 200

  Fly   200 ---DFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRM-SKESQRGRKRVTRLVVV 260
               .:.|   :.:..||..:|:||.||...|:.:|:::  :.:|:|: |.:.::..|:|||:|.:
Human   201 SGAWYTG---FIIYTFILGFLVPLTIICLCYLFIIIKV--KSSGIRVGSSKRKKSEKKVTRMVSI 260

  Fly   261 VVIAFASLWLPVQLILLLK-SLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAF 324
            ||..|...|||..:..:.. |:.:..|..|..:...|.  .|.|::||.||:||||||:||:|:|
Human   261 VVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVV--VLTYANSCANPILYAFLSDNFKKSF 323

  Fly   325  324
            Human   324  323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	100/300 (33%)
		TM helix 1	40..66	CDD:320224	10/25 (40%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	14/29 (48%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	9/28 (32%)
		TM helix 6	249..279	CDD:320224	11/29 (38%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
SSTR2	NP_001041.1	7tmA_SSTR2	44..323	CDD:320637	100/293 (34%)
		TM helix 1	45..71	CDD:320637	10/25 (40%)
		TM helix 2	78..104	CDD:320637	13/26 (50%)
		TM helix 3	115..145	CDD:320637	14/29 (48%)
		TM helix 4	157..179	CDD:320637	5/21 (24%)
		TM helix 5	205..234	CDD:320637	10/31 (32%)
		TM helix 6	249..279	CDD:320637	11/29 (38%)
		TM helix 7	291..316	CDD:320637	11/26 (42%)